ID Q7SYY7_XENLA Unreviewed; 91 AA.
AC Q7SYY7;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=High mobility group nucleosomal binding domain 2 L homeolog {ECO:0000313|RefSeq:NP_001079778.1};
DE SubName: Full=MGC64395 protein {ECO:0000313|EMBL:AAH54216.1};
GN Name=hmgn2.L {ECO:0000313|RefSeq:NP_001079778.1,
GN ECO:0000313|Xenbase:XB-GENE-1015278};
GN Synonyms=HMG-17 {ECO:0000313|RefSeq:NP_001079778.1}, hmgn2
GN {ECO:0000313|RefSeq:NP_001079778.1,
GN ECO:0000313|Xenbase:XB-GENE-1015278};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAH54216.1};
RN [1] {ECO:0000313|RefSeq:NP_001079778.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAH54216.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Whole {ECO:0000313|EMBL:AAH54216.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:NP_001079778.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Binds to the inner side of the nucleosomal DNA thus altering
CC the interaction between the DNA and the histone octamer. May be
CC involved in the process which maintains transcribable genes in a unique
CC chromatin conformation. {ECO:0000256|ARBA:ARBA00037490}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HMGN family.
CC {ECO:0000256|ARBA:ARBA00007696}.
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DR EMBL; BC054216; AAH54216.1; -; mRNA.
DR RefSeq; NP_001079778.1; NM_001086309.1.
DR DNASU; 379468; -.
DR GeneID; 379468; -.
DR KEGG; xla:379468; -.
DR AGR; Xenbase:XB-GENE-1015278; -.
DR CTD; 379468; -.
DR Xenbase; XB-GENE-1015278; hmgn2.L.
DR Proteomes; UP000186698; Chromosome 2L.
DR Bgee; 379468; Expressed in neurula embryo and 19 other cell types or tissues.
DR GO; GO:0000785; C:chromatin; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031492; F:nucleosomal DNA binding; IEA:InterPro.
DR InterPro; IPR000079; HMGN_fam.
DR PANTHER; PTHR23087:SF13; NON-HISTONE CHROMOSOMAL PROTEIN HMG-17; 1.
DR PANTHER; PTHR23087; NONHISTONE CHROMOSOMAL PROTEIN HMG; 1.
DR Pfam; PF01101; HMG14_17; 1.
DR PRINTS; PR00925; NONHISHMG17.
DR SMART; SM00527; HMG17; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000186698}.
FT REGION 1..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..65
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 91 AA; 9537 MW; E3BF65B6A77B2F40 CRC64;
MPKRKADGDS KVEKSKAKDE PQRQSARLSA KPAAPKPEPK PKKAAPPKKA DKAPKGKKGK
ADSGKDSSNA AENGEAKSDQ AQKAETTGDT K
//
