ID Q7TRD1_MOUSE Unreviewed; 311 AA.
AC Q7TRD1;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 150.
DE SubName: Full=Olfactory receptor Olfr901 {ECO:0000313|EMBL:AAP71377.1};
DE SubName: Full=Olfactory receptor family 8 subfamily B member 42 {ECO:0000313|Ensembl:ENSMUSP00000066714.2};
GN Name=Or8b42 {ECO:0000313|Ensembl:ENSMUSP00000066714.2,
GN ECO:0000313|MGI:MGI:3030735};
GN Synonyms=Olfr901 {ECO:0000313|EMBL:AAP71377.1,
GN ECO:0000313|MGI:MGI:3030735};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAP71377.1};
RN [1] {ECO:0000313|EMBL:AAP71377.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=14611657; DOI=10.1186/gb-2003-4-11-r71;
RA Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A.,
RA Walker M., Williams E.M., Trask B.J.;
RT "Odorant receptor expressed sequence tags demonstrate olfactory expression
RT of over 400 genes, extensive alternate splicing and unequal expression
RT levels.";
RL Genome Biol. 4:R71.1-R71.13(2003).
RN [2] {ECO:0000313|EMBL:AAP71377.1}
RP NUCLEOTIDE SEQUENCE.
RA Sanders K.;
RL Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000066714.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000066714.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [4] {ECO:0000313|Ensembl:ENSMUSP00000066714.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000066714.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AY318087; AAP71377.1; -; Genomic_DNA.
DR RefSeq; NP_001011806.1; NM_001011806.1.
DR RefSeq; XP_011240836.1; XM_011242534.1.
DR STRING; 10090.ENSMUSP00000150506; -.
DR PaxDb; 10090-ENSMUSP00000066714; -.
DR DNASU; 258028; -.
DR Ensembl; ENSMUST00000063716.2; ENSMUSP00000066714.2; ENSMUSG00000052058.4.
DR Ensembl; ENSMUST00000216502.3; ENSMUSP00000150507.2; ENSMUSG00000052058.4.
DR Ensembl; ENSMUST00000216644.2; ENSMUSP00000150506.2; ENSMUSG00000052058.4.
DR GeneID; 258028; -.
DR KEGG; mmu:258028; -.
DR UCSC; uc009owj.1; mouse.
DR AGR; MGI:3030735; -.
DR CTD; 258028; -.
DR MGI; MGI:3030735; Or8b42.
DR VEuPathDB; HostDB:ENSMUSG00000052058; -.
DR eggNOG; ENOG502T9M1; Eukaryota.
DR GeneTree; ENSGT01010000222320; -.
DR HOGENOM; CLU_012526_1_0_1; -.
DR OMA; MANTACM; -.
DR OrthoDB; 5317957at2759; -.
DR TreeFam; TF352753; -.
DR BioGRID-ORCS; 258028; 3 hits in 71 CRISPR screens.
DR Proteomes; UP000000589; Chromosome 9.
DR GO; GO:0016020; C:membrane; ISA:MGI.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR CDD; cd15405; 7tmA_OR8B-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PANTHER; PTHR48018; OLFACTORY RECEPTOR; 1.
DR PANTHER; PTHR48018:SF195; OLFACTORY RECEPTOR 901; 1.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Olfaction {ECO:0000256|ARBA:ARBA00022725};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:AAP71377.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 42..290
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 311 AA; 34848 MW; 1330C7C4E3C24D88 CRC64;
MASGNDSTTV KEFILLGLTQ QPELQLPFFF LFLGIYVVSI VGNLGLIVLI VLNPHLHTPM
YYFLFNLSFI DFCYSSVITP KMLVGFVKQN IISHAECMTQ LFFFAFFVID ECCILTAMSY
DRYVAICKPL LYKVTMSYQV CFMMTVSVYM MGFVGAIAHT ICMLRLTFCD GNIINHYMCD
IPPLLKLSCT NTSVNELVVF IVVGVNVIGP TLIIFTSYTL IIFNISHIRS TEGRSKAIST
CSSHIIAVSI FFGASAFMYL KPSPVGSVGE DKVSTVFYTI VGPMLNPFIY SLRNKDVHIA
LHKTLKKSML I
//
