ID Q7TUZ3_PROMM Unreviewed; 1347 AA.
AC Q7TUZ3;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=magnesium chelatase {ECO:0000256|ARBA:ARBA00012825};
DE EC=6.6.1.1 {ECO:0000256|ARBA:ARBA00012825};
GN Name=chlH {ECO:0000313|EMBL:CAE20990.1};
GN OrderedLocusNames=PMT_0815 {ECO:0000313|EMBL:CAE20990.1};
OS Prochlorococcus marinus (strain MIT 9313).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales;
OC Prochlorococcaceae; Prochlorococcus.
OX NCBI_TaxID=74547 {ECO:0000313|EMBL:CAE20990.1, ECO:0000313|Proteomes:UP000001423};
RN [1] {ECO:0000313|EMBL:CAE20990.1, ECO:0000313|Proteomes:UP000001423}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIT 9313 {ECO:0000313|Proteomes:UP000001423};
RX PubMed=12917642; DOI=10.1038/nature01947;
RA Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A.,
RA Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L.,
RA Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C.,
RA Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R.,
RA Chisholm S.W.;
RT "Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche
RT differentiation.";
RL Nature 424:1042-1047(2003).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O + Mg(2+) + protoporphyrin IX = ADP + 3 H(+) + Mg-
CC protoporphyrin IX + phosphate; Xref=Rhea:RHEA:13961,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:18420,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:57306,
CC ChEBI:CHEBI:60492, ChEBI:CHEBI:456216; EC=6.6.1.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001499};
CC -!- PATHWAY: Porphyrin-containing compound metabolism.
CC {ECO:0000256|ARBA:ARBA00023444}.
CC -!- SIMILARITY: Belongs to the Mg-chelatase subunit H family.
CC {ECO:0000256|ARBA:ARBA00010851}.
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DR EMBL; BX548175; CAE20990.1; -; Genomic_DNA.
DR RefSeq; WP_011130193.1; NC_005071.1.
DR KEGG; pmt:PMT_0815; -.
DR eggNOG; COG1429; Bacteria.
DR HOGENOM; CLU_002017_1_2_3; -.
DR OrthoDB; 9757976at2; -.
DR Proteomes; UP000001423; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016851; F:magnesium chelatase activity; IEA:UniProtKB-EC.
DR GO; GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR CDD; cd10150; CobN_like; 1.
DR InterPro; IPR011771; BchH.
DR InterPro; IPR003672; CobN/Mg_chltase.
DR InterPro; IPR022571; Mg_chelatase_H_N.
DR NCBIfam; TIGR02025; BchH; 1.
DR PANTHER; PTHR44119; MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC; 1.
DR PANTHER; PTHR44119:SF1; MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC; 1.
DR Pfam; PF02514; CobN-Mg_chel; 1.
DR Pfam; PF11965; DUF3479; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chlorophyll biosynthesis {ECO:0000256|ARBA:ARBA00023171};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Photosynthesis {ECO:0000256|ARBA:ARBA00022531};
KW Reference proteome {ECO:0000313|Proteomes:UP000001423}.
FT DOMAIN 25..186
FT /note="Magnesium chelatase subunit H N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11965"
SQ SEQUENCE 1347 AA; 149763 MW; 1A7159ED937634E6 CRC64;
MFTQVRSADR RVAPAENHSH QAVMKAVYLV LEPQYQSALS QAANSLNAQN GAIGVELSGY
LIEELRDPSN FADFQADVAE ADVFIASLIF IEDLAQKVVD AVTPHRERLK AIVVFPSMPE
VMRLNKLGTF TMAQLGQSDS VIANFMKKRK ESNGAGFQDA MLKLLNTLPN VLKYLPVDKA
QDARSFVLSF QYWLGGTPDN LRNFLLMLAD KYVFPATEGE DRPKLDIVEP EIFPDLGIWH
PMAPSMFEDL KEYLNWTTSR TDLSEKARKG PMIGLVLQRS HIVTGDDAHY VAVIQELEFR
GARVLPIFCG GLDFSKPVNA FFFDPVNPDQ PLVDGVVSLT GFALVGGPAR QDHPKAIESL
KRLSRPYMVA LPLVFQTTQE WEVSDLGLHP VQVALQIAIP ELDGAIEPIV LSGRDDATGK
AHTLQDRVDA IAERAIRWSS LRIKSRAEKK LAITIFSFPP DKGNVGSAAY LDVFGSIHRV
LEEMKAQGYD IQNLPKDSKA LMEAVINDPE ALEGAPELAI AHRMSVAEYE HLTPYSERLE
ENWGKPPGEL NSDGQNLLIY GRHFGNIFVG VQPTFGYEGD PMRLLYSRSA SPHHGFAAYY
TYLEKIWKAD AVLHFGTHGS LEFMPGKQMG MSETCYPDSL IGGLPNLYYY AANNPSEATI
AKRRGYASTI SYLTPPAENA GLYKGLKELG ELVGSYQQLR EGGRGVQIVN TIIETARQCN
LDRDVDLPEQ DAAELDLDQR DAVVGAVYSQ LMEIESRLLP CGLHTIGKPP TAEEAIATLV
SIAALEREDD GLRSLPGLLA EAIDRKIEDI YKGNDDGILA DVELNRTITE ASRVAVRAMV
QSLTGRDGRV NMKDNSNWYL DWFFNLLQRF GVTRPNAWLQ ACRKAGFGNI DSIELDKLFS
YLRGCLEKIC ADMEMQSLLR ALDGEYVLPG PGGDPIRNPG VLPSGKNIHA LDPQAIPTRA
AVAAAKGVVD KLIERQRQEQ GDWPETIACV LWGTDNIKTY GESLAQILWF IGVNPVPDSV
GRVNKLKLIP LEELGRPRID VVVNCSGVFR DLFINQMALI DQGVKMAAEA DEPLDQNFVR
KHSLEQAKEQ GTSLRDAACR VFSNSSGSYS SNVNLAVENS TWEEENELQE MYLSRKTFAF
NADNPGEMNQ NREVFESVMK TADVTFQNLD SAEISLTDVS HYFDSDPTNL IKGLRDDGKA
PASYIADTTT ANAQVRSLSE TIRLDSRTKL LNPKWYEGMV NSGYEGVREV AKRLNFTLGW
SATSGQVDNF VYEESNETFI NDPEMRKRLM ELNPHSFRRI VGTLLEVNGR GYWETSDENI
QQLQELYQEI EDRIEGVTTP DNQSSGE
//
