ID Q7USJ8_RHOBA Unreviewed; 462 AA.
AC Q7USJ8;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 24-JAN-2024, entry version 95.
DE RecName: Full=BON domain-containing protein {ECO:0000259|PROSITE:PS50914};
GN OrderedLocusNames=RB4459 {ECO:0000313|EMBL:CAD73798.1};
OS Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1).
OC Bacteria; Planctomycetota; Planctomycetia; Pirellulales; Pirellulaceae;
OC Rhodopirellula.
OX NCBI_TaxID=243090 {ECO:0000313|EMBL:CAD73798.1, ECO:0000313|Proteomes:UP000001025};
RN [1] {ECO:0000313|EMBL:CAD73798.1, ECO:0000313|Proteomes:UP000001025}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10527 / NCIMB 13988 / SH1
RC {ECO:0000313|Proteomes:UP000001025};
RX PubMed=12835416; DOI=10.1073/pnas.1431443100;
RA Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W.,
RA Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R.,
RA Reinhardt R.;
RT "Complete genome sequence of the marine planctomycete Pirellula sp. strain
RT 1.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX294140; CAD73798.1; -; Genomic_DNA.
DR RefSeq; NP_866112.1; NC_005027.1.
DR AlphaFoldDB; Q7USJ8; -.
DR STRING; 243090.RB4459; -.
DR EnsemblBacteria; CAD73798; CAD73798; RB4459.
DR KEGG; rba:RB4459; -.
DR PATRIC; fig|243090.15.peg.2078; -.
DR eggNOG; COG0668; Bacteria.
DR eggNOG; COG2823; Bacteria.
DR HOGENOM; CLU_037945_7_0_0; -.
DR InParanoid; Q7USJ8; -.
DR OrthoDB; 9809206at2; -.
DR Proteomes; UP000001025; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.1340.30; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR007055; BON_dom.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR008910; MSC_TM_helix.
DR InterPro; IPR045275; MscS_archaea/bacteria_type.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30221; SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR PANTHER; PTHR30221:SF1; SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR Pfam; PF04972; BON; 1.
DR Pfam; PF05552; MS_channel_1st_1; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR PROSITE; PS50914; BON; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001025};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 178..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 81..150
FT /note="BON"
FT /evidence="ECO:0000259|PROSITE:PS50914"
FT REGION 439..462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..462
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 462 AA; 51176 MW; 4BD2D7D03DC9CF90 CRC64;
MKNPSAISKR PSKMKTDFQM SGESRWSDWA YKTIRYVFVL VVMLCISVAA NRVSAQETSE
AEPVEDTNAP AETVSVQNIS DDDAIRDRLT KIFDSAKEAG WLSDAEVELQ SGIVTIRGQA
DTEEHRQWAE NVARKTEDVV AVINELSIDS AVDLASTREV VTKSLDSLWT DFLVRSPLLV
AALFVVLVTS LLSKLASWII HRLLDNRGMR TSLKDLVNQL SSIAIWIVGL LIATVVAFPG
MTPSKALTVL GLGSVAIGFA FKDIFENFFA GILILWGYPF DRGDFITCGD LTGEVKQITI
RNTLIRKLDG ELAVVPNASL FKNNVDVLTS QPQRRVRIIC GVAYDEDVDQ SRDVIKQAVQ
SCETVQGKRT VEVFAKEFAD SSINFEVAWW AGSKPLDIRR SRDEVVAAIK RDLDAAGIEI
PFPYRTLTFK NPEHIGFKTT ESVVENKGPG DHRSTPTEES ES
//
