ID Q7UUN6_RHOBA Unreviewed; 1302 AA.
AC Q7UUN6;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Probable integral membrane protein {ECO:0000313|EMBL:CAD73043.1};
GN OrderedLocusNames=RB3185 {ECO:0000313|EMBL:CAD73043.1};
OS Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1).
OC Bacteria; Planctomycetota; Planctomycetia; Pirellulales; Pirellulaceae;
OC Rhodopirellula.
OX NCBI_TaxID=243090 {ECO:0000313|EMBL:CAD73043.1, ECO:0000313|Proteomes:UP000001025};
RN [1] {ECO:0000313|EMBL:CAD73043.1, ECO:0000313|Proteomes:UP000001025}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10527 / NCIMB 13988 / SH1
RC {ECO:0000313|Proteomes:UP000001025};
RX PubMed=12835416; DOI=10.1073/pnas.1431443100;
RA Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W.,
RA Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R.,
RA Reinhardt R.;
RT "Complete genome sequence of the marine planctomycete Pirellula sp. strain
RT 1.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; BX294138; CAD73043.1; -; Genomic_DNA.
DR RefSeq; NP_865359.1; NC_005027.1.
DR RefSeq; WP_011119226.1; NC_005027.1.
DR STRING; 243090.RB3185; -.
DR EnsemblBacteria; CAD73043; CAD73043; RB3185.
DR KEGG; rba:RB3185; -.
DR PATRIC; fig|243090.15.peg.1468; -.
DR eggNOG; COG1033; Bacteria.
DR HOGENOM; CLU_009844_0_0_0; -.
DR InParanoid; Q7UUN6; -.
DR OrthoDB; 2112773at2; -.
DR Proteomes; UP000001025; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001025};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 475..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 501..525
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 545..564
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 576..597
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 661..679
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1068..1088
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1100..1123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1177..1200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1206..1230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 483..599
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 1104..1231
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 400..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 611..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1247..1302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..420
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 611..625
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1285..1302
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1302 AA; 142347 MW; 9E8011765E374B37 CRC64;
MTADSTKPSF LERPGPWGLT VALLILMGFF FFMPSAFRAA RMGLKNKEND VKDWLPSDFP
ETAELDWFAD HFAGESFVLL TWEGCNVGDQ RLRLFEDKLL HESANYREQL AADEAWGENA
LSLAEVQTRV RARELGEELE LLPPGQDLTN WGGEDEKWLA SADGTWYYIK PDGKLFRWEE
SMNGPAALVR KFNKSIGEYE LKGQFVTAFG EPSTTERINP FYNDPMLLCA PLFQTVQTGA
TIAEQLAAEG GPLWPIDLTD VTKKPIVAKR LAMERLTGTL FAPAVPHEFD WTAESFIEKL
PEESRSGLPA DAPETIERAL ETFVVERLDG DREKLATSLT QTQTDAWYAV YDALGVEPPP
RLTCLLVTLT DLAKDNLAFA VGRGTLGTPQ GRLLQLAQQS GIQPPLPPSS APPPFNREPP
ESIGGMPPLR MGGPPIDNIA IDEEGTITLV RLVGYCILVG VLLSYFCFRS FKVTIMLFVV
GGSAAMLSMS MVGWTGGRVD AILMSMPSLV YVLGLSGSIH VINYYRDEVR FRGRRGAATR
ALKHAALPCT LAALTTAIGL ASLFTSNLKP ISNFGLYSAI GVISTLGVLF SYLPAALETF
SPQFGQDKAE ERKRLAAEKR KTEATVDTNS GSTPTKGAVS GELELAAWWA GVGRWITGNH
AIVSIACIVG LAIASLGLFK ITTSVQLLKL FDPQARILRD YAWLEDHFGN LVPMEIVVRM
PPEIQRPERL ASASTEEEGD DQDRLSDPIS LSLLERIEAV ARIRKVVTRS LGEEGIAKVG
QASSMDTFIA PLPDVSNGWS NTRSQFNSRL NESRDELLTS DYVKIEKNGP LKDSELWRLS
LRVSALSDVD YGLFINELKD AVDPVVQAYR VRAKLLRELQ QPDGTQLPKA KVLVLGAQNV
VELDSANLVT TDEISGERVV DQRAIFLSTL RELLGNERIR QSWIDPDAED AIAKPTDENW
DRRIAAADVV IDLAGLSFQA STSKTVAATE PVESYAAGAE RLISAMEVIS RPIPKHILSL
DKVADGQPNR LPVFELDEPA TPQVIYTGVV PVVYKAQRTL LGSLVESILL AFVLIGFVMI
VLLNPGSFPG QWLAPSNLRA GFAAGAVSMI PNVFPVLLVF GVMGHLRTAV DIGTMMTASV
AMGVAVDDTI HFLTWFRQFL EEGKSRKEAV IETYRRVGPA MTQTTIVGGL GLFIFAMSTF
TPTQRFGTLM LVMLAAALIG DLILLPALLA GPLGKVFKPR HDHLGKPAFD PGQSVSAESP
SSLDAVQPER PTEGIVVTED TPVLKVHKPP TRTESNHPSR KG
//
