ID Q7VWJ8_BORPE Unreviewed; 342 AA.
AC Q7VWJ8;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE SubName: Full=Regulator (SIS family) {ECO:0000313|EMBL:CAE42494.1};
GN OrderedLocusNames=BP2217 {ECO:0000313|EMBL:CAE42494.1};
OS Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=257313 {ECO:0000313|EMBL:CAE42494.1, ECO:0000313|Proteomes:UP000002676};
RN [1] {ECO:0000313|Proteomes:UP000002676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tohama I / ATCC BAA-589 / NCTC 13251
RC {ECO:0000313|Proteomes:UP000002676};
RX PubMed=12910271; DOI=10.1038/ng1227;
RA Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R.,
RA Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L.,
RA Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A.,
RA Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T.,
RA Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S.,
RA Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E.,
RA Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M.,
RA Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S.,
RA Barrell B.G., Maskell D.J.;
RT "Comparative analysis of the genome sequences of Bordetella pertussis,
RT Bordetella parapertussis and Bordetella bronchiseptica.";
RL Nat. Genet. 35:32-40(2003).
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DR EMBL; BX640417; CAE42494.1; -; Genomic_DNA.
DR RefSeq; NP_880862.1; NC_002929.2.
DR RefSeq; WP_003818661.1; NZ_CP039022.1.
DR AlphaFoldDB; Q7VWJ8; -.
DR STRING; 257313.BP2217; -.
DR PaxDb; 257313-BP2217; -.
DR GeneID; 69602115; -.
DR KEGG; bpe:BP2217; -.
DR PATRIC; fig|257313.5.peg.2393; -.
DR eggNOG; COG1737; Bacteria.
DR HOGENOM; CLU_055769_1_3_4; -.
DR Proteomes; UP000002676; Chromosome.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05013; SIS_RpiR; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR000281; HTH_RpiR.
DR InterPro; IPR047640; RpiR-like.
DR InterPro; IPR035472; RpiR-like_SIS.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR30514; GLUCOKINASE; 1.
DR PANTHER; PTHR30514:SF18; RPIR-FAMILY TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF01380; SIS; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51071; HTH_RPIR; 1.
DR PROSITE; PS51464; SIS; 1.
PE 4: Predicted;
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Reference proteome {ECO:0000313|Proteomes:UP000002676};
KW Transferase {ECO:0000256|ARBA:ARBA00022777}.
FT DOMAIN 25..101
FT /note="HTH rpiR-type"
FT /evidence="ECO:0000259|PROSITE:PS51071"
FT DOMAIN 151..301
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
SQ SEQUENCE 342 AA; 36407 MW; 3BD5310A4430BB24 CRC64;
MFFIFSEIYH VFFILFRAMP PTPAPSMLET LQSLLDDLPA ELQRAARWVA AHPAEVGLWS
MRRQAQAVGV APATMLRLAR AAGCGSYEDF RAPFQQALTA AGGSGWRDRA AELQAAQDAG
AAPGHDVLTG LQTQAIGSIR ALNPPAAFDA AARTLLAAGQ VGFLGTRSAF GIAHQMRYAY
QLVRRNGLLI DGLGGAPAEQ IDNLQAGDAL VAISQAPYPA ATVHLARQAS QRGVTVVALT
DDPLSPLALE AGHVLLFARP ERERVYAEPA QRGPGSFFHT TAGLLGLAEH LIARLAACGG
ETALARLAEI EARLQAEQVY WSPAHARRDK ARPGRGMPRE AA
//
