ID Q7VYJ1_BORPE Unreviewed; 1139 AA.
AC Q7VYJ1;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE RecName: Full=TM0106 family RecB-like nuclease {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=BP1345 {ECO:0000313|EMBL:CAE41637.1};
OS Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=257313 {ECO:0000313|EMBL:CAE41637.1, ECO:0000313|Proteomes:UP000002676};
RN [1] {ECO:0000313|Proteomes:UP000002676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tohama I / ATCC BAA-589 / NCTC 13251
RC {ECO:0000313|Proteomes:UP000002676};
RX PubMed=12910271; DOI=10.1038/ng1227;
RA Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R.,
RA Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L.,
RA Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A.,
RA Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T.,
RA Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S.,
RA Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E.,
RA Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M.,
RA Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S.,
RA Barrell B.G., Maskell D.J.;
RT "Comparative analysis of the genome sequences of Bordetella pertussis,
RT Bordetella parapertussis and Bordetella bronchiseptica.";
RL Nat. Genet. 35:32-40(2003).
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DR EMBL; BX640415; CAE41637.1; -; Genomic_DNA.
DR RefSeq; NP_880097.1; NC_002929.2.
DR RefSeq; WP_010930312.1; NZ_CP039022.1.
DR AlphaFoldDB; Q7VYJ1; -.
DR STRING; 257313.BP1345; -.
DR PaxDb; 257313-BP1345; -.
DR GeneID; 69601257; -.
DR KEGG; bpe:BP1345; -.
DR PATRIC; fig|257313.5.peg.1445; -.
DR eggNOG; COG1112; Bacteria.
DR eggNOG; COG2251; Bacteria.
DR HOGENOM; CLU_008884_0_0_4; -.
DR Proteomes; UP000002676; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd17934; DEXXQc_Upf1-like; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR019993; RecB_nuclease_TM0106_put.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR038720; YprB_RNase_H-like_dom.
DR NCBIfam; TIGR03491; TM0106 family RecB-like putative nuclease; 1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF525; HELICASE SENATAXIN-RELATED; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF13604; AAA_30; 1.
DR Pfam; PF13482; RNase_H_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022806};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022806};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022806};
KW Reference proteome {ECO:0000313|Proteomes:UP000002676}.
FT DOMAIN 321..498
FT /note="YprB ribonuclease H-like"
FT /evidence="ECO:0000259|Pfam:PF13482"
FT DOMAIN 924..1105
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
SQ SEQUENCE 1139 AA; 125325 MW; D1DD45BEFE892A78 CRC64;
MQQLGATRRY AASDLVGFLA CEHLTQLDLR ALDAGQAPAA ADDEQMALVQ AKGQAHEQAW
LERLRARHPD LADVTRAGPD LAARLAATRA AMAAGAPVIY QAALCHGPYV GHADFLLRTE
CPSALGDYGY EALDTKLARS PRASFVLQLS FYAWLLEHAQ GVAPRSMHVV LGSGRELALR
VADYAHYLRQ VLRRFEAAIA AEPAPPTYPE PCEHCPQCRW RVACEARRVA DDHLSLVAGM
SRQQARRLNA QGVATLAQLG ALPEHAQVAG IEAGTLQRLR AQAALQWRAR VDGARHYELL
AAQDEGPRGL ARLPRPDPGD MFFDMEGDPL EDGGLEYLFG LYVIDDGAER FVPFWAHDRR
QEKQAFEAFM DFVAERLRRH PDAHIYHYAP YEATALKKLM SLHGTREAEV DHLLRAGKLV
DLYRVVREGL RISEPSYSIK YVERFYLPRR AGEVTNAGAS IVYYERWKAT DEPRLLQDIA
DYNRDDVIST WRLRDWLCGI RPAALPWHNE AGQQDLDAAR AVIGEMTEAE RRLLPYRAAL
ADDLPADEAA WSPRDAFRAL AWHLLDFHRR EQKPAWWAWF ARAEATDGEL IEDAECLGGL
ARDDAAPPVR QAQSLRYTYR YPAQETKLRT GARCTDVRTG ASLANLVVDP HARLASFTCS
ARKPAPPPRM ALGPAAPVNN KELVNAVFRY GDAVCRAPDG MSMPMRAVDA LLRREPPRIR
GLARGAPLVA PHAELLPQVL DVVARMDETT LFLQGPPGAG KTYTGSRVLL QLLRAGRRVA
VSSNSHHAIN NLLRGLERLA EREGFALRGA KKSTSAGDDS CLGGAQIEDV FDNKDVDPAR
HQLVAGTAWL FARPEFEQAF DYLFVDEAGQ VSLANLVAMG QCARNIVLLG DQMQLGQPSQ
GTHPGRSGES ALDYLLDGQA TIAASQGVFL DTSYRMHPEI CGFISEAIYD GRLRAAPATA
AHRLLLDEAA GRELPAHGIR YVPVPHDGNT QSSREEAARV AELCALLLRQ RHVDEAGAPA
PLTLDDILFV APYNVQVNTL RAALPDGARV GTVDKFQGQE AQVVIVSMAT SSGDYLPRDL
EFLFSRNRLN VAISRARTLA ILVASPALTA VRCRSAEQMA LVNTLCWVAE TGSASPYQV
//
