ID Q7VZY9_BORPE Unreviewed; 271 AA.
AC Q7VZY9;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 113.
DE SubName: Full=Probable transcriptional regulator {ECO:0000313|EMBL:CAE41034.1};
GN OrderedLocusNames=BP0727 {ECO:0000313|EMBL:CAE41034.1};
OS Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=257313 {ECO:0000313|EMBL:CAE41034.1, ECO:0000313|Proteomes:UP000002676};
RN [1] {ECO:0000313|Proteomes:UP000002676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tohama I / ATCC BAA-589 / NCTC 13251
RC {ECO:0000313|Proteomes:UP000002676};
RX PubMed=12910271; DOI=10.1038/ng1227;
RA Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R.,
RA Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L.,
RA Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A.,
RA Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T.,
RA Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S.,
RA Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E.,
RA Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M.,
RA Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S.,
RA Barrell B.G., Maskell D.J.;
RT "Comparative analysis of the genome sequences of Bordetella pertussis,
RT Bordetella parapertussis and Bordetella bronchiseptica.";
RL Nat. Genet. 35:32-40(2003).
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DR EMBL; BX640413; CAE41034.1; -; Genomic_DNA.
DR RefSeq; NP_879551.1; NC_002929.2.
DR RefSeq; WP_010929980.1; NZ_CP039022.1.
DR AlphaFoldDB; Q7VZY9; -.
DR STRING; 257313.BP0727; -.
DR PaxDb; 257313-BP0727; -.
DR GeneID; 69600683; -.
DR KEGG; bpe:BP0727; -.
DR PATRIC; fig|257313.5.peg.775; -.
DR eggNOG; COG1414; Bacteria.
DR HOGENOM; CLU_062618_0_1_4; -.
DR Proteomes; UP000002676; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF34; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002676};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 26..88
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 89..271
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 271 AA; 29483 MW; F87DCE717DDF7100 CRC64;
MRRSIVNSEL GVRSPTEEEL EDPLFVQAAA RTLQVLSAFH RAVRPMSLDE IAEASGVGRS
STQRILNTLR VLGYVERSDG GRGYVPGIRI LDHALDYLRL NTLISRASPV LLDLRRNALE
RVDLSVFDDL RLVYASRLQS KRETFFATLV GHSVPTFCTA GGRAILSHLP GAEVDDIIAR
SDRAPFTDKT ITALREIRKK VEQARVSGYA VTIEEVLVGE IGIGVAVLGA DGRPVGAIHI
AGSLSEWTPE AFTARFAPLA VEAATAINRL S
//
