ID Q7W8A2_BORPA Unreviewed; 266 AA.
AC Q7W8A2;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Type III secretion protein {ECO:0000313|EMBL:CAE37537.1};
GN Name=bscT {ECO:0000313|EMBL:CAE37537.1};
GN OrderedLocusNames=BPP2237 {ECO:0000313|EMBL:CAE37537.1};
OS Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=257311 {ECO:0000313|EMBL:CAE37537.1, ECO:0000313|Proteomes:UP000001421};
RN [1] {ECO:0000313|Proteomes:UP000001421}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=12822 / ATCC BAA-587 / NCTC 13253
RC {ECO:0000313|Proteomes:UP000001421};
RX PubMed=12910271; DOI=10.1038/ng1227;
RA Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R.,
RA Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L.,
RA Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A.,
RA Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T.,
RA Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S.,
RA Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E.,
RA Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M.,
RA Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S.,
RA Barrell B.G., Maskell D.J.;
RT "Comparative analysis of the genome sequences of Bordetella pertussis,
RT Bordetella parapertussis and Bordetella bronchiseptica.";
RL Nat. Genet. 35:32-40(2003).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC ECO:0000256|RuleBase:RU362072}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU362072}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FliR/MopE/SpaR family.
CC {ECO:0000256|ARBA:ARBA00009772, ECO:0000256|RuleBase:RU362072}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX640429; CAE37537.1; -; Genomic_DNA.
DR RefSeq; WP_010928437.1; NC_002928.3.
DR AlphaFoldDB; Q7W8A2; -.
DR GeneID; 69421621; -.
DR KEGG; bpa:BPP2237; -.
DR HOGENOM; CLU_063626_0_2_4; -.
DR Proteomes; UP000001421; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR InterPro; IPR002010; T3SS_IM_R.
DR InterPro; IPR006304; T3SS_SpaR/YscT.
DR NCBIfam; TIGR01401; fliR_like_III; 1.
DR PANTHER; PTHR30065; FLAGELLAR BIOSYNTHETIC PROTEIN FLIR; 1.
DR PANTHER; PTHR30065:SF1; SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAR; 1.
DR Pfam; PF01311; Bac_export_1; 1.
DR PRINTS; PR00953; TYPE3IMRPROT.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU362072};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362072};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362072};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362072}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362072"
FT TRANSMEM 81..105
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362072"
FT TRANSMEM 130..154
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362072"
FT TRANSMEM 184..206
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362072"
FT TRANSMEM 218..239
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362072"
SQ SEQUENCE 266 AA; 28952 MW; C03D3277E18C43B2 CRC64;
MHTEFNFVEA KVFLGTLAMT QPRILAAMLF LPMFNRQFLP GPLRYAVGAC LGLIVVPQLA
PQYAALDIGW PRLLALLAKE AMVGMFLGWL AALPFWIFEA IGFVIDNQRG ASLGAIPNPA
TGNDSSPLGI LFNLGFMVFF LTAGGFGLFA TMLYDSFGLW NIWAWWPSMP AQGAVRMLDQ
FSGFAARVLL LASPAIVAMF LAELGLALIS RFAPQLQVFF LALPVKSALV LLVLVLYMAT
LFQYAGEILG SVGRIVPFLH SAWPGS
//
