ID   Q7YR17_MYSTU            Unreviewed;       397 AA.
AC   Q7YR17;
DT   01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2003, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=von Willebrand factor {ECO:0000256|ARBA:ARBA00016619};
DE   Flags: Fragment;
GN   Name=vWF {ECO:0000313|EMBL:AAO62361.1};
OS   Mystacina tuberculata (New Zealand lesser short-tailed bat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Mystacinidae;
OC   Mystacina.
OX   NCBI_TaxID=94961 {ECO:0000313|EMBL:AAO62361.1};
RN   [1] {ECO:0000313|EMBL:AAO62361.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=12878467; DOI=10.1016/S1055-7903(03)00117-9;
RA   Teeling E.C., Madsen O., Murphy W.J., Springer M.S., O'Brien S.J.;
RT   "Nuclear gene sequences confirm an ancient link between New Zealand's
RT   short-tailed bat and South American noctilionoid bats.";
RL   Mol. Phylogenet. Evol. 28:308-319(2003).
CC   -!- SUBUNIT: Multimeric. Interacts with F8.
CC       {ECO:0000256|ARBA:ARBA00025858}.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC       matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR   EMBL; AY245421; AAO62361.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q7YR17; -.
DR   GO; GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.
DR   CDD; cd01450; vWFA_subfamily_ECM; 2.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR   InterPro; IPR032361; VWA_N2.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR   PANTHER; PTHR24020:SF70; PH DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00092; VWA; 2.
DR   Pfam; PF16164; VWA_N2; 1.
DR   PRINTS; PR00453; VWFADOMAIN.
DR   SMART; SM00327; VWA; 2.
DR   SUPFAM; SSF53300; vWA-like; 2.
DR   PROSITE; PS50234; VWFA; 2.
PE   4: Predicted;
KW   Blood coagulation {ECO:0000256|ARBA:ARBA00023084};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Hemostasis {ECO:0000256|ARBA:ARBA00022696};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          34..210
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   DOMAIN          255..397
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAO62361.1"
FT   NON_TER         397
FT                   /evidence="ECO:0000313|EMBL:AAO62361.1"
SQ   SEQUENCE   397 AA;  44455 MW;  9FD4BEBE66A4144E CRC64;
     EVPPTEAPFS STTPYVEDIP EPPLHDFYCS KLLDLVFLLD GSSNLSEAEF EVLKAFVVSM
     MERLRISQKW IRVALVEYHK GSHAYIQLRD RKRPSDLRRI ASQVKYTGST VASISEVLKY
     TLFQIFGKID RPEASRIVLL LTASQEPRNM VRTVMQYVKN LKRKKVIVVP VGIGPHVNPN
     QIRAIEKQAS ENKAFLLSSV DELEQRRDEM ISYLCDLAPE PPAPTQPPPV AQVTVAAEPL
     GTLSPGPNRR PMLLDVVFVL EGSDQIGEAN FNRSKEFLEK VIQRMDVGQD SVHVTVLQYS
     YTVTVESTFR EAQSKGDILQ RVREIRYQGG NSTNTGLALQ YVSEHSFLAS QGDRELAPNL
     VYMVTGNPAS DVIRRMPGDI QVVPIGVGCH ADVHELE
//