ID Q7Z536_HUMAN Unreviewed; 149 AA.
AC Q7Z536;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE SubName: Full=Mucin 1, cell surface associated {ECO:0000313|Ensembl:ENSP00000484730.1};
DE SubName: Full=Mucin short variant SV10 {ECO:0000313|EMBL:AAP97029.1};
GN Name=MUC1 {ECO:0000313|EMBL:AAP97029.1,
GN ECO:0000313|Ensembl:ENSP00000484730.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|EMBL:AAP97029.1};
RN [1] {ECO:0000313|EMBL:AAP97029.1}
RP NUCLEOTIDE SEQUENCE.
RA Zhang L.X., Lu H.J.;
RL Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSP00000484730.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16710414; DOI=10.1038/nature04727;
RA Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A.,
RA Scott C.E., Howe K.L., Woodfine K., Spencer C.C., Jones M.C., Gillson C.,
RA Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.,
RA Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C.,
RA Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W.,
RA Ashwell R.I., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H.,
RA Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C.,
RA Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R.,
RA Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A.,
RA Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.,
RA Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V.,
RA Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.,
RA Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R.,
RA Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D.,
RA Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A.,
RA Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M.,
RA Loveland J., Lovell J., Lush M.J., Lyne R., Martin S.,
RA Mashreghi-Mohammadi M., Matthews L., Matthews N.S., McLaren S., Milne S.,
RA Mistry S., Moore M.J., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A.,
RA Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S.,
RA Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G.,
RA Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S.,
RA Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A.,
RA Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L.,
RA Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z.,
RA Coulson A., Vaudin M., Sulston J.E., Durbin R., Hubbard T., Wooster R.,
RA Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V.,
RA Beck S., Rogers J., Bentley D.R., Banerjee R., Bryant S.P., Burford D.C.,
RA Burrill W.D., Clegg S.M., Dhami P., Dovey O., Faulkner L.M., Gribble S.M.,
RA Langford C.F., Pandian R.D., Porter K.M., Prigmore E.;
RT "The DNA sequence and biological annotation of human chromosome 1.";
RL Nature 441:315-321(2006).
RN [3] {ECO:0000313|EMBL:AAP97029.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=22941036; DOI=10.1007/s00262-012-1325-2;
RA Zhang L., Vlad A., Milcarek C., Finn O.J.;
RT "Human mucin MUC1 RNA undergoes different types of alternative splicing
RT resulting in multiple isoforms.";
RL Cancer Immunol. Immunother. 62:423-435(2013).
RN [4] {ECO:0000313|Ensembl:ENSP00000484730.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC234582; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AY327600; AAP97029.1; -; mRNA.
DR MEROPS; S71.001; -.
DR Antibodypedia; 1298; 5132 antibodies from 55 providers.
DR Ensembl; ENST00000471283.5; ENSP00000484730.1; ENSG00000185499.17.
DR UCSC; uc057lnb.1; human.
DR HGNC; HGNC:7508; MUC1.
DR VEuPathDB; HostDB:ENSG00000185499; -.
DR GeneTree; ENSGT00710000106874; -.
DR HOGENOM; CLU_1749011_0_0_1; -.
DR ChiTaRS; MUC1; human.
DR Proteomes; UP000005640; Chromosome 1.
DR Bgee; ENSG00000185499; Expressed in pylorus and 172 other cell types or tissues.
DR InterPro; IPR036364; SEA_dom_sf.
DR PANTHER; PTHR10006:SF19; MUCIN-1; 1.
DR PANTHER; PTHR10006; MUCIN-1-RELATED; 1.
DR SUPFAM; SSF82671; SEA domain; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:Q7Z536,
KW ECO:0007829|MaxQB:Q7Z536};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..149
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014588710"
FT REGION 26..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 149 AA; 16263 MW; 7CB4B9632BB7EEEC CRC64;
MTPGTQSPFF LLLLLTVLTV VTGSGHASST PGGEKETSAT QRSSVPSSTE KNAFNSSLED
PSTDYYQELQ RDISEMFLQI YKQGGFLGLS NIKFSLGLGC QAGASRCWCW SVFWLRWPLS
ISLPWLSVSA AERTTGSWTS FQPGIPTIL
//
