ID   Q7ZZY0_CHICK            Unreviewed;       249 AA.
AC   Q7ZZY0;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 2.
DT   24-JAN-2024, entry version 76.
DE   RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE            EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
DE   Flags: Fragment;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031 {ECO:0000313|EMBL:AAP03050.2};
RN   [1] {ECO:0000313|EMBL:AAP03050.2}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Pancreas {ECO:0000313|EMBL:AAP03050.2};
RX   PubMed=15878833; DOI=10.1016/j.cbpc.2005.02.006;
RA   Berradi H., Taouis M., Cassy S., Rideau N.;
RT   "Glucokinase in chicken (Gallus gallus). Partial cDNA cloning,
RT   immunodetection and activity determination.";
RL   Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 141:129-139(2005).
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 1/4.
CC       {ECO:0000256|ARBA:ARBA00004888}.
CC   -!- SIMILARITY: Belongs to the hexokinase family.
CC       {ECO:0000256|RuleBase:RU362007}.
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DR   EMBL; AY256906; AAP03050.2; -; mRNA.
DR   AlphaFoldDB; Q7ZZY0; -.
DR   VEuPathDB; HostDB:geneid_430370; -.
DR   PhylomeDB; Q7ZZY0; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR   GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   GO; GO:0001678; P:intracellular glucose homeostasis; IEA:InterPro.
DR   Gene3D; 3.40.367.20; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR001312; Hexokinase.
DR   InterPro; IPR022673; Hexokinase_C.
DR   PANTHER; PTHR19443; HEXOKINASE; 1.
DR   PANTHER; PTHR19443:SF3; HEXOKINASE-4; 1.
DR   Pfam; PF03727; Hexokinase_2; 1.
DR   PRINTS; PR00475; HEXOKINASE.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR   PROSITE; PS51748; HEXOKINASE_2; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding {ECO:0000256|RuleBase:RU362007};
KW   Glycolysis {ECO:0000256|RuleBase:RU362007};
KW   Kinase {ECO:0000256|RuleBase:RU362007, ECO:0000313|EMBL:AAP03050.2};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362007};
KW   Transferase {ECO:0000256|RuleBase:RU362007}.
FT   DOMAIN          30..246
FT                   /note="Hexokinase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03727"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAP03050.2"
FT   NON_TER         249
FT                   /evidence="ECO:0000313|EMBL:AAP03050.2"
SQ   SEQUENCE   249 AA;  27694 MW;  094D36B06FED2407 CRC64;
     GDFEMDVVAM VNDTVATMIS CYYEDHRREV GMIVGTGCNA CYMEEMHNVE LVEGDEGRMC
     VNTEWGAFGA SGELDEFLLE YDRVVDETSL NPGQQLYEKI IGGKYMGEIV RLVLLRLVDE
     NLLFSGQACE KLKTRGAFET RFVSQVESDS GDRKQIYNIL TAFGLLPSGS DCDIVRMVCE
     SVSTRAAQMC SAGLAGVINR MRESRSQETL KITVGVDGSV YKLHPSFKDR FHATVRQLTP
     GCDITFIQS
//