ID Q821D3_CHLCV Unreviewed; 293 AA.
AC Q821D3;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE SubName: Full=Geranyltranstransferase {ECO:0000313|EMBL:AAP05748.1};
GN Name=ispA {ECO:0000313|EMBL:AAP05748.1};
GN OrderedLocusNames=CCA_01009 {ECO:0000313|EMBL:AAP05748.1};
OS Chlamydia caviae (strain ATCC VR-813 / DSM 19441 / 03DC25 / GPIC)
OS (Chlamydophila caviae).
OC Bacteria; Chlamydiota; Chlamydiia; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=227941 {ECO:0000313|EMBL:AAP05748.1, ECO:0000313|Proteomes:UP000002193};
RN [1] {ECO:0000313|EMBL:AAP05748.1, ECO:0000313|Proteomes:UP000002193}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC VR-813 / DSM 19441 / GPIC
RC {ECO:0000313|Proteomes:UP000002193};
RX PubMed=12682364; DOI=10.1093/nar/gkg321;
RA Read T.D., Myers G.S.A., Brunham R.C., Nelson W.C., Paulsen I.T.,
RA Heidelberg J.F., Holtzapple E.K., Khouri H.M., Federova N.B., Carty H.A.,
RA Umayam L.A., Haft D.H., Peterson J.D., Beanan M.J., White O.,
RA Salzberg S.L., Hsia R.-C., McClarty G., Rank R.G., Bavoil P.M.,
RA Fraser C.M.;
RT "Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC):
RT examining the role of niche-specific genes in the evolution of the
RT Chlamydiaceae.";
RL Nucleic Acids Res. 31:2134-2147(2003).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; AE015925; AAP05748.1; -; Genomic_DNA.
DR RefSeq; WP_011006961.1; NC_003361.3.
DR AlphaFoldDB; Q821D3; -.
DR STRING; 227941.CCA_01009; -.
DR KEGG; cca:CCA_01009; -.
DR eggNOG; COG0142; Bacteria.
DR HOGENOM; CLU_014015_0_1_0; -.
DR OrthoDB; 9805316at2; -.
DR Proteomes; UP000002193; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR43281; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR43281:SF1; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:AAP05748.1}.
SQ SEQUENCE 293 AA; 32503 MW; C1257D8D2DCBD054 CRC64;
MVVMNMFETY RIMIEAGIES SLEEFGSKGL SVRAPVEYAL TSGGKRIRPM LVCMIAKGLD
MSRDVLDAAL AIEFIHTSTL IADDLPCMDD DDERRGRPTV HKAFDEASAL LASYALIPAA
YSRIRLNAKK LKSQGVDPKE VDIAYDIISD VTDKNFGVNG VLGGQYEDMF FKNDGPEYVQ
SIINKKTGAL FEIACVSGWL FGGGDPLCVP QIIEFSQTFG LLFQMKDDIL DIHQDGQDVG
LNYALLFGLD AAKDLLNSSM DKCMILLKHL KQHGLKDTSE LEMLIEYMGI RDY
//
