ID Q82DF0_STRAW Unreviewed; 580 AA.
AC Q82DF0;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:BAC72744.1};
GN ORFNames=SAVERM_5032 {ECO:0000313|EMBL:BAC72744.1};
OS Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS 14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC72744.1, ECO:0000313|Proteomes:UP000000428};
RN [1] {ECO:0000313|EMBL:BAC72744.1, ECO:0000313|Proteomes:UP000000428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX PubMed=11572948; DOI=10.1073/pnas.211433198;
RA Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M.;
RT "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT deducing the ability of producing secondary metabolites.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN [2] {ECO:0000313|EMBL:BAC72744.1, ECO:0000313|Proteomes:UP000000428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX PubMed=12692562; DOI=10.1038/nbt820;
RA Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M., Omura S.;
RT "Complete genome sequence and comparative analysis of the industrial
RT microorganism Streptomyces avermitilis.";
RL Nat. Biotechnol. 21:526-531(2003).
CC -!- SIMILARITY: Belongs to the LytR/CpsA/Psr (LCP) family.
CC {ECO:0000256|ARBA:ARBA00006068}.
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DR EMBL; BA000030; BAC72744.1; -; Genomic_DNA.
DR RefSeq; WP_010986437.1; NZ_JZJK01000077.1.
DR AlphaFoldDB; Q82DF0; -.
DR KEGG; sma:SAVERM_5032; -.
DR eggNOG; COG1316; Bacteria.
DR HOGENOM; CLU_016455_0_0_11; -.
DR OrthoDB; 9782542at2; -.
DR Proteomes; UP000000428; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.2390; -; 1.
DR Gene3D; 3.40.630.190; LCP protein; 1.
DR InterPro; IPR027381; LytR/CpsA/Psr_C.
DR InterPro; IPR004474; LytR_CpsA_psr.
DR NCBIfam; TIGR00350; lytR_cpsA_psr; 1.
DR PANTHER; PTHR33392; POLYISOPRENYL-TEICHOIC ACID--PEPTIDOGLYCAN TEICHOIC ACID TRANSFERASE TAGU; 1.
DR PANTHER; PTHR33392:SF6; POLYISOPRENYL-TEICHOIC ACID--PEPTIDOGLYCAN TEICHOIC ACID TRANSFERASE TAGU; 1.
DR Pfam; PF13399; LytR_C; 1.
DR Pfam; PF03816; LytR_cpsA_psr; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000428};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 177..340
FT /note="Cell envelope-related transcriptional attenuator"
FT /evidence="ECO:0000259|Pfam:PF03816"
FT DOMAIN 448..540
FT /note="LytR/CpsA/Psr regulator C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13399"
FT REGION 1..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..81
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 580 AA; 61654 MW; C953221A13B2FC73 CRC64;
MVQSSVRRKG ARPRDRQTGE PGWDDSLYDD NGEPVQDGRG SGRGGGSAQG GGDGDGPPDE
AKGHSRHGGG RRRGGKGDGG GGRPRRRRRV LRWSATVLAV LILGTAGAGY LYYQHLNDNI
KKDDLYLGDD KDRAAKPKAN AAGQTPLNIL LIGSDARDSA ANQKLGGAKD TYGGTPRADV
QMLLHLSADR SNMSVVSMPR DTLLEIPKCT DPKTSHTYAA ITYPTMTNNS LGRGGPGCTV
ATWEKFTDIH IDHFMMVDFA GVVSMADAIG GVPVCVDANI YSHTSTGHGS GLKLKDGTTS
IKGKQALQWL RTRYGFEDGS DIGRTKAQHQ YMNSMVRQLR ENATLSNPNK LRKLAETATN
ALTVDDGLGT VSKLYDLSKE LKKVPTSRIT MTTMPWVYSS DGNRVLPKPN DAAKVFRLLR
EDIALDGKDK KKSPAQKAVA PAHADDKIAV QVQNGTRTSA LAPVGGRANA MAQLLVGKGF
TGAAADSSTV LSEDKTVIRY PSADLKGDAQ RVAKSLGVPL SSVEKSASVS GVTLIVGGDW
RSGTTYKAAE DDDTTPASAK LDKGSDTGAC MHVDPDYTWS
//
