ID Q82RB7_STRAW Unreviewed; 588 AA.
AC Q82RB7;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 121.
DE SubName: Full=Reverse transcriptase homolog similar to GII intron {ECO:0000313|EMBL:BAC67935.1};
GN ORFNames=SAVERM_226 {ECO:0000313|EMBL:BAC67935.1};
OS Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS 14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC67935.1, ECO:0000313|Proteomes:UP000000428};
RN [1] {ECO:0000313|EMBL:BAC67935.1, ECO:0000313|Proteomes:UP000000428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX PubMed=11572948; DOI=10.1073/pnas.211433198;
RA Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M.;
RT "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT deducing the ability of producing secondary metabolites.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN [2] {ECO:0000313|EMBL:BAC67935.1, ECO:0000313|Proteomes:UP000000428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX PubMed=12692562; DOI=10.1038/nbt820;
RA Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M., Omura S.;
RT "Complete genome sequence and comparative analysis of the industrial
RT microorganism Streptomyces avermitilis.";
RL Nat. Biotechnol. 21:526-531(2003).
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DR EMBL; BA000030; BAC67935.1; -; Genomic_DNA.
DR RefSeq; WP_010981662.1; NC_003155.5.
DR AlphaFoldDB; Q82RB7; -.
DR KEGG; sma:SAVERM_226; -.
DR eggNOG; COG1403; Bacteria.
DR eggNOG; COG3344; Bacteria.
DR HOGENOM; CLU_013584_15_4_11; -.
DR Proteomes; UP000000428; Chromosome.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00085; HNHc; 1.
DR CDD; cd01651; RT_G2_intron; 1.
DR Gene3D; 1.10.30.50; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR030931; Group_II_RT_mat.
DR InterPro; IPR002711; HNH.
DR InterPro; IPR003615; HNH_nuc.
DR InterPro; IPR013597; Mat_intron_G2.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR025960; RVT_N.
DR NCBIfam; TIGR04416; group_II_RT_mat; 1.
DR PANTHER; PTHR34047:SF8; GROUP II INTRON-ASSOCIATED OPEN READING FRAME; 1.
DR PANTHER; PTHR34047; NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF08388; GIIM; 1.
DR Pfam; PF01844; HNH; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF13655; RVT_N; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:BAC67935.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000428};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:BAC67935.1};
KW Transferase {ECO:0000313|EMBL:BAC67935.1}.
FT DOMAIN 100..333
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT REGION 568..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 588 AA; 67532 MW; 7A0C0827A0DB9BB3 CRC64;
MTELAIAEPR MNGPEGDTEF WHSIDWSREE TSVKRLRQRI FRAAREGDMK QVRNLQKLMR
RSRANTLTSV RRVCQVSTGK KTAGIDGQKA LSPEKRGKTA RQILADPMSH PQPVRRVYIP
KANGKRRPLG IPVIRDRVDQ ARFKNALEPE WEARFEARSY GFRPGRGAWD AIEMIFNVAG
RRTAKRLWVL DADLSAAFDH ISHQHLMDSV GLFPGRRQIQ QWLRAGVMED GRFVSTPEGT
PQGGVISPLL MNIALHGMGE VIGANRPWNA KTTSPTLVRY ADDFVVFCTT ENEAIKAKQD
LAAWLEPRGL SFNEEKTRVV HLSSGVDFLG FNVGRFRQKL IIKPSRDALQ RARKRISTTA
RENSGSPTES LVRALSPFVR GWSTYYRTVC SKETFNLLDA HTFEVLKRWA MRRHRRKPWG
WIKRRYWGTF QPGRSSKWVF GTPEHYLPQA SWMPIQRHTL VKDDASPDDQ ELEEYWGNRR
RKRIQAVGEP KKILSLAYRQ RGLCPRCGLD LIDGVGFDPD DVQDWANWFT GSLRAIHVHH
LTYRSKGGSD HPSNLELIHT TCHRQAHAGD RKYDAHRRPQ ASLSRMRG
//
