ID Q82TH8_NITEU Unreviewed; 616 AA.
AC Q82TH8;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase domain 2 (EAL) {ECO:0000313|EMBL:CAD85820.1};
GN OrderedLocusNames=NE1909 {ECO:0000313|EMBL:CAD85820.1};
OS Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC
OS 14298).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosomonas.
OX NCBI_TaxID=228410 {ECO:0000313|EMBL:CAD85820.1, ECO:0000313|Proteomes:UP000001416};
RN [1] {ECO:0000313|EMBL:CAD85820.1, ECO:0000313|Proteomes:UP000001416}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298
RC {ECO:0000313|Proteomes:UP000001416};
RX PubMed=12700255; DOI=10.1128/JB.185.9.2759-2773.2003;
RA Chain P., Lamerdin J., Larimer F., Regala W., Land M., Hauser L.,
RA Hooper A., Klotz M., Norton J., Sayavedra-Soto L., Arciero D., Hommes N.,
RA Whittaker M., Arp D.;
RT "Complete genome sequence of the ammonia-oxidizing bacterium and obligate
RT chemolithoautotroph Nitrosomonas europaea.";
RL J. Bacteriol. 185:2759-2773(2003).
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DR EMBL; AL954747; CAD85820.1; -; Genomic_DNA.
DR RefSeq; WP_011112446.1; NC_004757.1.
DR AlphaFoldDB; Q82TH8; -.
DR STRING; 228410.NE1909; -.
DR KEGG; neu:NE1909; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_50_4; -.
DR OrthoDB; 9813903at2; -.
DR PhylomeDB; Q82TH8; -.
DR Proteomes; UP000001416; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 2.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 2.
DR Pfam; PF00672; HAMP; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 2.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001416};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 93..145
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 181..336
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 345..598
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 616 AA; 68025 MW; 0EEF5E040C91B37E CRC64;
MKLIIARYAI RVARFTARGG NFIPEGGKIK GRGLNSIPIR FTLMALVFTA LCTFLQYHYV
LPLIESGTSD SIVVVAILLS ISLPAAITYF AANKLTNTIR ELNKSTDAIA AGDFDRPVDV
DCACEVGSLA DSFRAMVNRL NSNIVRINTL AYTDAVTGLP NRAVVSHVLD LAARMRGSAD
CKGALMFIDL DGFKRINDTL GHEGGDELLR QVSRRVIEKG FNLTRGQIEN CTTAFGELRQ
TCPEKLVFAR FAGDEFVAIM PGEFHRRVLE KYAADILKAV NEPFLVSDNE LRIGASIGIA
RVTSDSDDPR QLLINADIAM YSAKESGKNQ YRFFDESLKN IAVERSQIEA DLRKAIEEDM
LDMHYQPKLN AQTLQVTGVE ALVRWKHPQK GAIPPARFVG IAEQCGLMPA LGTNILRMVA
RQARAWQEVG MPMPIAVNVS AVQFERSGIA NEILAILEQH AVDPLLIEIE LTESMIMSDF
ATAKSRLEQL REAGAQISID DFGTGYSNLY QLSHLPFNVL KIDKSLVDDI GKNSKSEAIV
TAIVQMVHSL GHRVVAEGVE THEQYAFLRK ARCDQVQGYL FGRPMPAHEL IEWVSDHASD
NGSMNNTLIE KVSRVA
//
