ID Q82VN8_NITEU Unreviewed; 148 AA.
AC Q82VN8;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE RecName: Full=Universal stress protein {ECO:0000256|PIRNR:PIRNR006276};
GN OrderedLocusNames=NE1028 {ECO:0000313|EMBL:CAD84939.1};
OS Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC
OS 14298).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosomonas.
OX NCBI_TaxID=228410 {ECO:0000313|EMBL:CAD84939.1, ECO:0000313|Proteomes:UP000001416};
RN [1] {ECO:0000313|EMBL:CAD84939.1, ECO:0000313|Proteomes:UP000001416}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298
RC {ECO:0000313|Proteomes:UP000001416};
RX PubMed=12700255; DOI=10.1128/JB.185.9.2759-2773.2003;
RA Chain P., Lamerdin J., Larimer F., Regala W., Land M., Hauser L.,
RA Hooper A., Klotz M., Norton J., Sayavedra-Soto L., Arciero D., Hommes N.,
RA Whittaker M., Arp D.;
RT "Complete genome sequence of the ammonia-oxidizing bacterium and obligate
RT chemolithoautotroph Nitrosomonas europaea.";
RL J. Bacteriol. 185:2759-2773(2003).
RN [2] {ECO:0007829|PDB:2PFS, ECO:0007829|PDB:3TNJ}
RP X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) IN COMPLEX WITH AMP.
RX PubMed=23745136; DOI=10.1111/eva.12057;
RA Tkaczuk K.L., A Shumilin I., Chruszcz M., Evdokimova E., Savchenko A.,
RA Minor W.;
RT "Structural and functional insight into the universal stress protein
RT family.";
RL Evol. Appl. 6:434-449(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR006276}.
CC -!- SIMILARITY: Belongs to the universal stress protein A family.
CC {ECO:0000256|ARBA:ARBA00008791, ECO:0000256|PIRNR:PIRNR006276}.
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DR EMBL; AL954747; CAD84939.1; -; Genomic_DNA.
DR RefSeq; WP_011111637.1; NC_004757.1.
DR PDB; 2PFS; X-ray; 2.25 A; A=1-148.
DR PDB; 3TNJ; X-ray; 2.00 A; A=1-148.
DR PDBsum; 2PFS; -.
DR PDBsum; 3TNJ; -.
DR AlphaFoldDB; Q82VN8; -.
DR SMR; Q82VN8; -.
DR STRING; 228410.NE1028; -.
DR KEGG; neu:NE1028; -.
DR eggNOG; COG0589; Bacteria.
DR HOGENOM; CLU_049301_11_3_4; -.
DR OrthoDB; 5295044at2; -.
DR PhylomeDB; Q82VN8; -.
DR EvolutionaryTrace; Q82VN8; -.
DR Proteomes; UP000001416; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR CDD; cd00293; USP_Like; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR006015; Universal_stress_UspA.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR46268; STRESS RESPONSE PROTEIN NHAX; 1.
DR PANTHER; PTHR46268:SF6; UNIVERSAL STRESS PROTEIN A-RELATED; 1.
DR Pfam; PF00582; Usp; 1.
DR PIRSF; PIRSF006276; UspA; 1.
DR PRINTS; PR01438; UNVRSLSTRESS.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:2PFS, ECO:0007829|PDB:3TNJ};
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR006276};
KW Nucleotide-binding {ECO:0007829|PDB:3TNJ};
KW Reference proteome {ECO:0000313|Proteomes:UP000001416}.
FT DOMAIN 4..144
FT /note="UspA"
FT /evidence="ECO:0000259|Pfam:PF00582"
FT BINDING 10
FT /ligand="AMP"
FT /ligand_id="ChEBI:CHEBI:456215"
FT /evidence="ECO:0007829|PDB:3TNJ"
FT BINDING 40
FT /ligand="AMP"
FT /ligand_id="ChEBI:CHEBI:456215"
FT /evidence="ECO:0007829|PDB:3TNJ"
FT BINDING 42
FT /ligand="AMP"
FT /ligand_id="ChEBI:CHEBI:456215"
FT /evidence="ECO:0007829|PDB:3TNJ"
FT BINDING 114
FT /ligand="AMP"
FT /ligand_id="ChEBI:CHEBI:456215"
FT /evidence="ECO:0007829|PDB:3TNJ"
FT BINDING 128
FT /ligand="AMP"
FT /ligand_id="ChEBI:CHEBI:456215"
FT /evidence="ECO:0007829|PDB:3TNJ"
SQ SEQUENCE 148 AA; 16402 MW; 6005182663F764EE CRC64;
MSVYHHILLA VDFSSEDSQV VQKVRNLASQ IGARLSLIHV LDNIPMPDTP YGTAIPLDTE
TTYDAMLDVE KQKLSQIGNT LGIDPAHRWL VWGEPREEII RIAEQENVDL IVVGSHGRHG
LALLLGSTAN SVLHYAKCDV LAVRLRDD
//
