ID Q837L0_ENTFA Unreviewed; 321 AA.
AC Q837L0;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 120.
DE SubName: Full=Oxidoreductase, Gfo/Idh/MocA family {ECO:0000313|EMBL:AAO80639.1};
GN OrderedLocusNames=EF_0827 {ECO:0000313|EMBL:AAO80639.1};
OS Enterococcus faecalis (strain ATCC 700802 / V583).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=226185 {ECO:0000313|EMBL:AAO80639.1, ECO:0000313|Proteomes:UP000001415};
RN [1] {ECO:0000313|EMBL:AAO80639.1, ECO:0000313|Proteomes:UP000001415}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700802 / V583 {ECO:0000313|Proteomes:UP000001415};
RX PubMed=12663927; DOI=10.1126/science.1080613;
RA Paulsen I., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R., Read T.D.,
RA Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA Dodson R.J., Umayam L., Brinkac L., Beanan M., Daugherty S., DeBoy R.T.,
RA Durkin S., Kolonay J., Madupu R., Nelson W., Vamathevan J., Tran B.,
RA Upton J., Hansen T., Shetty J., Khouri H., Utterback T., Radune D.,
RA Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT faecalis.";
RL Science 299:2071-2074(2003).
RN [2] {ECO:0007829|PDB:3E9M}
RP X-RAY CRYSTALLOGRAPHY (2.70 ANGSTROMS) OF 2-321.
RA Damodharan L., K Burley S.K., Swaminathan S.;
RT "Crystal Structure of an oxidoreductase from Enterococcus faecalis.";
RL Submitted (AUG-2008) to the PDB data bank.
CC -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family.
CC {ECO:0000256|ARBA:ARBA00010928}.
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DR EMBL; AE016830; AAO80639.1; -; Genomic_DNA.
DR RefSeq; NP_814569.1; NC_004668.1.
DR PDB; 3E9M; X-ray; 2.70 A; A/B/C/D=2-321.
DR PDBsum; 3E9M; -.
DR AlphaFoldDB; Q837L0; -.
DR SMR; Q837L0; -.
DR STRING; 226185.EF_0827; -.
DR DNASU; 1199720; -.
DR EnsemblBacteria; AAO80639; AAO80639; EF_0827.
DR KEGG; efa:EF0827; -.
DR PATRIC; fig|226185.45.peg.2761; -.
DR eggNOG; COG0673; Bacteria.
DR HOGENOM; CLU_023194_7_2_9; -.
DR EvolutionaryTrace; Q837L0; -.
DR Proteomes; UP000001415; Chromosome.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR22604; OXIDOREDUCTASES; 1.
DR PANTHER; PTHR22604:SF105; TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE; 1.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:3E9M};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001415}.
FT DOMAIN 5..121
FT /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01408"
FT DOMAIN 135..314
FT /note="Gfo/Idh/MocA-like oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02894"
SQ SEQUENCE 321 AA; 35749 MW; 44A026BFE3F626E6 CRC64;
MDKIRYGIMS TAQIVPRFVA GLRESAQAEV RGIASRRLEN AQKMAKELAI PVAYGSYEEL
CKDETIDIIY IPTYNQGHYS AAKLALSQGK PVLLEKPFTL NAAEAEELFA IAQEQGVFLM
EAQKSVFLPI TQKVKATIQE GGLGEILWVQ SVTAYPNVDH IPWFYSREAG GGALHGSGSY
PLQYLQYVLG KEIQEVTGTA TYQQGATDSQ CNLALKFAEG TLGNIFINVG LKIPSEMTIC
GTKGQIVIPN FWKTDCAYYT DAQGNTVKWS EQFTSEFTYE INHVNQCLQD KKLTSPVMTK
ELTIATVKIV ESFYQEWFDN E
//
