ID Q84DH3_ENTCL Unreviewed; 238 AA.
AC Q84DH3; A0A0M7D111;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 130.
DE RecName: Full=Succinate dehydrogenase iron-sulfur subunit {ECO:0000256|ARBA:ARBA00022131, ECO:0000256|RuleBase:RU361237};
DE EC=1.3.5.1 {ECO:0000256|ARBA:ARBA00012792, ECO:0000256|RuleBase:RU361237};
GN Name=sdhB {ECO:0000313|EMBL:AAO39688.1};
GN ORFNames=DA103_14645 {ECO:0000313|EMBL:PTM35050.1}, DM877_02910
GN {ECO:0000313|EMBL:RXW30574.1}, DP202_16300
GN {ECO:0000313|EMBL:RAZ65505.1}, EGK68_06315
GN {ECO:0000313|EMBL:RSB32574.1}, EGM92_11985
GN {ECO:0000313|EMBL:TAT63226.1}, J5T73_003441
GN {ECO:0000313|EMBL:HAZ4815201.1}, N5E88_00270
GN {ECO:0000313|EMBL:MDH1477929.1}, NCTC10005_06094
GN {ECO:0000313|EMBL:STQ13283.1}, SAMEA2273318_00694
GN {ECO:0000313|EMBL:CZU53428.1};
OS Enterobacter cloacae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
OX NCBI_TaxID=550 {ECO:0000313|EMBL:AAO39688.1};
RN [1] {ECO:0000313|EMBL:AAO39688.1}
RP NUCLEOTIDE SEQUENCE.
RA Lohrke S., Liu S., Roberts D.;
RT "Mutation of an sdhA homolog in Enterobacter cloacae results in reduced
RT colonization of cucumber but does not affect biocontrol of damping-off.";
RL Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AAO39688.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=17768262; DOI=10.1099/mic.0.2006/005538-0;
RA Liu S., Hu X., Lohrke S.M., Baker C.J., Buyer J.S., de Souza J.T.,
RA Roberts D.P.;
RT "Role of sdhA and pfkA and catabolism of reduced carbon during colonization
RT of cucumber roots by Enterobacter cloacae.";
RL Microbiology 153:3196-3209(2007).
RN [3] {ECO:0000313|EMBL:CZU53428.1, ECO:0000313|Proteomes:UP000076008}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=e1252 {ECO:0000313|Proteomes:UP000076008}, and E1252
RC {ECO:0000313|EMBL:CZU53428.1};
RG Pathogen Informatics;
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:HAZ4815201.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C041 {ECO:0000313|EMBL:HAZ4815201.1};
RX PubMed=30286803;
RA Souvorov A., Agarwala R., Lipman D.J.;
RT "SKESA: strategic k-mer extension for scrupulous assemblies.";
RL Genome Biol. 19:153-153(2018).
RN [5] {ECO:0000313|EMBL:PTM35050.1, ECO:0000313|Proteomes:UP000241614}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=amazonensis {ECO:0000313|Proteomes:UP000241614}, and
RC Amazonensis {ECO:0000313|EMBL:PTM35050.1};
RA Astolfi M.C.T., Carvalho E.B.D.S., Lacerda L.B., Pinto M.V., Nogueira V.B.,
RA Barros A.M., Astolfi-Filho S.;
RT "Genome sequencing reveals highly heavy metal resistance and biotechnology
RT application of the novel Enterobacter cloacae amazonensis isolated from
RT wastewater river in Manaus - Amazonas.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:RAZ65505.1, ECO:0000313|Proteomes:UP000251576}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=99B3 {ECO:0000313|EMBL:RAZ65505.1,
RC ECO:0000313|Proteomes:UP000251576};
RA Jousset A.B., Oueslati S., Bernabeu S., Takissian J., Creton E., Vogel A.,
RA Cotellon G., Bonnin R.A., Dortet L., Naas T.;
RT "ACT-28, a chromosomally-encoded AmpC with carbapenemase activity from
RT Enterobacter kobei.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|EMBL:RXW30574.1, ECO:0000313|Proteomes:UP000290875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GEO_4_Eff_A {ECO:0000313|EMBL:RXW30574.1,
RC ECO:0000313|Proteomes:UP000290875};
RA Mathys D.A., Mollenkopf D.F., Feicht S.M., Adams R.J., Albers A.L.,
RA Grooters S.V., Stuever D.M., Daniels J.B., Wittum T.E.;
RT "Carbapenemase-producing Enterobacteriaceae present in wastewater treatment
RT plant effluent and nearby surface waters in the US.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|EMBL:STQ13283.1, ECO:0000313|Proteomes:UP000255106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10005 {ECO:0000313|EMBL:STQ13283.1,
RC ECO:0000313|Proteomes:UP000255106};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [9] {ECO:0000313|EMBL:RSB32574.1, ECO:0000313|Proteomes:UP000275321}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC_073 {ECO:0000313|EMBL:RSB32574.1,
RC ECO:0000313|Proteomes:UP000275321};
RA D'Souza A.W., Potter R.F., Wallace M., Shupe A., Patel S., Sun S., Gul D.,
RA Kwon J.H., Andleeb S., Burnham C.-A.D., Dantas G.;
RT "Transmission dynamics of multidrug resistant bacteria on intensive care
RT unit surfaces.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN [10] {ECO:0000313|EMBL:TAT63226.1, ECO:0000313|Proteomes:UP000293139}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PLV-MS02 {ECO:0000313|EMBL:TAT63226.1,
RC ECO:0000313|Proteomes:UP000293139};
RA Lata P., Verma P., Marchica J., Srivastava N., Maurya S.K., Sahoo M.K.;
RT "ESBL producing Enterobacter cloacae genome sequencing and assembly.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN [11] {ECO:0000313|EMBL:HAZ4815201.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C041 {ECO:0000313|EMBL:HAZ4815201.1};
RG NCBI Pathogen Detection Project;
RL Submitted (MAR-2021) to the EMBL/GenBank/DDBJ databases.
RN [12] {ECO:0000313|EMBL:MDH1477929.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GD03711 {ECO:0000313|EMBL:MDH1477929.1};
RA Diorio-Toth L.;
RT "Intensive care unit water sources are persistently colonized with multi-
RT drug resistant bacteria and are the site of extensive horizontal gene
RT transfer of antibiotic resistance genes.";
RL Submitted (SEP-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a quinone + succinate = a quinol + fumarate;
CC Xref=Rhea:RHEA:40523, ChEBI:CHEBI:24646, ChEBI:CHEBI:29806,
CC ChEBI:CHEBI:30031, ChEBI:CHEBI:132124; EC=1.3.5.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000030,
CC ECO:0000256|RuleBase:RU361237};
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000256|RuleBase:RU361237};
CC Note=Binds 1 [2Fe-2S] cluster. {ECO:0000256|RuleBase:RU361237};
CC -!- COFACTOR:
CC Name=[3Fe-4S] cluster; Xref=ChEBI:CHEBI:21137;
CC Evidence={ECO:0000256|RuleBase:RU361237};
CC Note=Binds 1 [3Fe-4S] cluster. {ECO:0000256|RuleBase:RU361237};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|RuleBase:RU361237};
CC Note=Binds 1 [4Fe-4S] cluster. {ECO:0000256|RuleBase:RU361237};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle.
CC {ECO:0000256|ARBA:ARBA00005163}.
CC -!- SIMILARITY: Belongs to the succinate dehydrogenase/fumarate reductase
CC iron-sulfur protein family. {ECO:0000256|ARBA:ARBA00009433,
CC ECO:0000256|RuleBase:RU361237}.
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DR EMBL; AY194228; AAO39688.1; -; Genomic_DNA.
DR EMBL; FJXR01000003; CZU53428.1; -; Genomic_DNA.
DR EMBL; DADOIZ010000009; HAZ4815201.1; -; Genomic_DNA.
DR EMBL; JAOCIY010000001; MDH1477929.1; -; Genomic_DNA.
DR EMBL; PZPP01000014; PTM35050.1; -; Genomic_DNA.
DR EMBL; QMDH01000029; RAZ65505.1; -; Genomic_DNA.
DR EMBL; RHWT01000005; RSB32574.1; -; Genomic_DNA.
DR EMBL; QJSL01000002; RXW30574.1; -; Genomic_DNA.
DR EMBL; UGJB01000004; STQ13283.1; -; Genomic_DNA.
DR EMBL; RQJF01000753; TAT63226.1; -; Genomic_DNA.
DR RefSeq; WP_008501090.1; NZ_WNXG01000157.1.
DR GeneID; 83674091; -.
DR KEGG; eclg:EC036_12540; -.
DR PATRIC; fig|550.124.peg.4740; -.
DR OMA; DGQYFGP; -.
DR OrthoDB; 9804391at2; -.
DR Proteomes; UP000076008; Unassembled WGS sequence.
DR Proteomes; UP000241614; Unassembled WGS sequence.
DR Proteomes; UP000251576; Unassembled WGS sequence.
DR Proteomes; UP000255106; Unassembled WGS sequence.
DR Proteomes; UP000275321; Unassembled WGS sequence.
DR Proteomes; UP000290875; Unassembled WGS sequence.
DR Proteomes; UP000293139; Unassembled WGS sequence.
DR Proteomes; UP000868535; Unassembled WGS sequence.
DR Proteomes; UP001161707; Unassembled WGS sequence.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0051538; F:3 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0102040; F:fumarate reductase (menaquinone); IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008177; F:succinate dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR009051; Helical_ferredxn.
DR InterPro; IPR004489; Succ_DH/fum_Rdtase_Fe-S.
DR InterPro; IPR025192; Succ_DH/fum_Rdtase_N.
DR NCBIfam; TIGR00384; dhsB; 1.
DR PANTHER; PTHR11921:SF29; SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11921; SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN; 1.
DR Pfam; PF13085; Fer2_3; 1.
DR Pfam; PF13534; Fer4_17; 1.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
PE 3: Inferred from homology;
KW 2Fe-2S {ECO:0000256|ARBA:ARBA00022714, ECO:0000256|RuleBase:RU361237};
KW 3Fe-4S {ECO:0000256|ARBA:ARBA00023291, ECO:0000256|RuleBase:RU361237};
KW 4Fe-4S {ECO:0000256|RuleBase:RU361237};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU361237};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014, ECO:0000256|RuleBase:RU361237};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361237};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CZU53428.1};
KW Tricarboxylic acid cycle {ECO:0000256|ARBA:ARBA00022532}.
FT DOMAIN 1..97
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
FT DOMAIN 139..169
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 238 AA; 26713 MW; 5C5D6485C9FE1A55 CRC64;
MKLEFSVYRY NPDVDDAPRM QDYTLEAEEG RDMMLLDALI QLKEKDPTLS FRRSCREGVC
GSDGVNMNGK NGLACITPIS ALQRPGQKIV IRPLPGLPVV RDLVVDMGQF YAQYEKIKPY
LLNNGQNPPA REHLQSPEQR EKLDGLYECI LCACCSTSCP SFWWNPDKFI GPAGLLAAYR
FLIDSRDTET DSRLEGLSDA FSVFRCHSIM NCVSVCPKGL NPTRAIGHIK SMLLQRSA
//
