ID   Q84XA6_CATRO            Unreviewed;       430 AA.
AC   Q84XA6;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 66.
DE   SubName: Full=Cytochrome P450 71D2 {ECO:0000313|EMBL:AAO32823.1};
DE   Flags: Fragment;
GN   Name=CYP71D2 {ECO:0000313|EMBL:AAO32823.1};
OS   Catharanthus roseus (Madagascar periwinkle) (Vinca rosea).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae;
OC   Catharanthinae; Catharanthus.
OX   NCBI_TaxID=4058 {ECO:0000313|EMBL:AAO32823.1};
RN   [1] {ECO:0000313|EMBL:AAO32823.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Schroeder J., Schroeder G.;
RT   "P450 of the CYP71 family expressed in Catharanthus roseus cell suspension
RT   cultures.";
RL   Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413;
CC         Evidence={ECO:0000256|ARBA:ARBA00001971};
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR   EMBL; AY192574; AAO32823.1; -; mRNA.
DR   AlphaFoldDB; Q84XA6; -.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   CDD; cd11072; CYP71-like; 1.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   PANTHER; PTHR47953:SF5; OS02G0186300 PROTEIN; 1.
DR   PANTHER; PTHR47953; OS08G0105600 PROTEIN; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   2: Evidence at transcript level;
KW   Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW   Metal-binding {ECO:0000256|RuleBase:RU000461};
KW   Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000461}.
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAO32823.1"
SQ   SEQUENCE   430 AA;  48666 MW;  73CDCCC6B201CCFD CRC64;
     KLGGFNTIVA SSPRMAKEVL KTHDLSFLNR PIIQATKILC YDNSALVFSQ YGDSWRQMRK
     IFVLELLSTK RVRSFQPIRQ DEGSRLVSLI KESVGKSIDL SEKIKLYTTS MVARAAFGKV
     NDAGVTFLKL VTEAAEVAEG FDPADMFPSY KFLNVFFNSR SNLLKIHGKT DMILEEMIDE
     HIKSHQMGKK ANGENGEEDV IDILLSIKDS GDLGISHWMN NVKALIFDMF SAGTETSSAT
     VEWAMTELMK NPSVMRKAQD EVRQAFKGKK TIDESDLEEL KYLKLVVKEV LRLHPFAPLL
     VPRECREACQ IDGYDIPVKT RVFVNVWAIG RDEKYWKDPE SFIPERFEDN SLDFTGNNFE
     YLPFGCGRRI CPGMTFGLAN VHLVLALLLY HFNWKLPPGV NDIDMAERPG LGASKKHGLV
     LVPSFYQPSF
//