ID Q86DS4_DROSI Unreviewed; 363 AA.
AC Q86DS4;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 24-JAN-2024, entry version 85.
DE SubName: Full=Hsc-70-interacting protein-like protein {ECO:0000313|EMBL:AAP31291.1};
DE Flags: Fragment;
OS Drosophila simulans (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7240 {ECO:0000313|EMBL:AAP31291.1};
RN [1] {ECO:0000313|EMBL:AAP31291.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=92.9 {ECO:0000313|EMBL:AAP31291.1};
RA Bettencourt B.R., Lerman D.N., Feder M.E.;
RT "Escaping gene conversion: Adaptive molecular evolution of Hsp70 trans-
RT regulators.";
RL Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FAM10 family.
CC {ECO:0000256|ARBA:ARBA00009015}.
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DR EMBL; AY274368; AAP31291.1; -; Genomic_DNA.
DR AlphaFoldDB; Q86DS4; -.
DR EnsemblMetazoa; FBtr0216561; FBpp0215053; FBgn0066170.
DR Bgee; FBgn0066170; Expressed in embryo and 3 other cell types or tissues.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd14438; Hip_N; 1.
DR Gene3D; 1.10.260.100; -; 1.
DR Gene3D; 6.10.250.3420; -; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR034649; Hip_N.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45883; HSC70-INTERACTING PROTEIN; 1.
DR PANTHER; PTHR45883:SF2; HSC70-INTERACTING PROTEIN; 1.
DR Pfam; PF18253; HipN; 1.
DR Pfam; PF13414; TPR_11; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT DOMAIN 2..40
FT /note="Hsp70-interacting protein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18253"
FT REPEAT 119..152
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 56..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..270
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAP31291.1"
FT NON_TER 363
FT /evidence="ECO:0000313|EMBL:AAP31291.1"
SQ SEQUENCE 363 AA; 39711 MW; 55FFD362A239716D CRC64;
GDLKKLKYFI DYALENPTFL NMPQLQFVKD FVEKFGGTVP PGQFNGGSAG GKCPFGGDAG
AKANEPANAS VDSEDEKSLS DPESDVELDM EGVIEADSDP AQPMGNYSKK ATEEEVEQAS
ELRAQAASAY GQQKFDEAIA LYTKAIELSP GNALFHAKRG QAFLKLKKPN ACIRDCDMAL
ELNSDLAAGY KFRGRARRLL GDFELAAHDL RQACKLDFDE ETDEWLKEVT PNAKKIEQHR
VKQERRQAER KIKERQRDQR RARKEQEKHN VSSGGSSGEF PPGAPGNITI SDILGFMQDP
EASAAIQDIL SNPGNITKYA SNPKIIDLLK KMVPGFDVGA AFAQAAEKAG EPSEPKPKKD
SAD
//
