ID Q86IH2_DICDI Unreviewed; 588 AA.
AC Q86IH2; Q559C7;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE RecName: Full=Purple acid phosphatase N-terminal domain-containing protein {ECO:0000259|Pfam:PF16656};
GN ORFNames=DDB_G0272965 {ECO:0000313|EMBL:EAL71120.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL71120.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL71120.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL71120.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=12097910; DOI=10.1038/nature00847;
RG Dictyostelium Genome Sequencing Consortium;
RA Glockner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2] {ECO:0000313|EMBL:EAL71120.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL71120.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL71120.1}.
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DR EMBL; AAFI02000008; EAL71120.1; -; Genomic_DNA.
DR RefSeq; XP_644889.1; XM_639797.1.
DR AlphaFoldDB; Q86IH2; -.
DR SMR; Q86IH2; -.
DR STRING; 44689.Q86IH2; -.
DR PaxDb; 44689-DDB0217061; -.
DR GeneID; 8618568; -.
DR KEGG; ddi:DDB_G0272965; -.
DR dictyBase; DDB_G0272965; -.
DR eggNOG; KOG1378; Eukaryota.
DR HOGENOM; CLU_464180_0_0_1; -.
DR InParanoid; Q86IH2; -.
DR OMA; ENHYHLY; -.
DR PhylomeDB; Q86IH2; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR039331; PPA-like.
DR InterPro; IPR008963; Purple_acid_Pase-like_N.
DR InterPro; IPR015914; Purple_acid_Pase_N.
DR PANTHER; PTHR22953; ACID PHOSPHATASE RELATED; 1.
DR PANTHER; PTHR22953:SF119; PUR_AC_PHOSPH_N DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF16656; Pur_ac_phosph_N; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF49363; Purple acid phosphatase, N-terminal domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002195};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 186..299
FT /note="Purple acid phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16656"
SQ SEQUENCE 588 AA; 67112 MW; DE4EFBB1A76CF323 CRC64;
MSATFNDISF RHLFFLASLG ICLAIIVAVM IGFFLYGFIK YVKRGLSKKD GARYGGYLAW
EVFWVGTPLF VLMASAFNQI HWALAWVLMV IILQSGFMNI MKRSPDYKND LKFKGKIDNY
FRSLINGLSK FGKRNSILVF IAFVIGSFIS SFMMYDLCIG IHPFRVSSRY SRKSLGESCP
SGEICNFILT VPENLSNSII VGWHSNDEPI GSFAYYDTTS HSDYFKDGLV MKIENFKNLY
GFSVNGTYFE MDNIRQEEQR YVSWADITGL TPSTVYYIVV GIEKSDGELI FYPERKFRTA
PSDGTPYNFI TGGDMGMTGT GESLSINAAM VEPLFVMLGG DVAYDSGFDS CYRCWDEWFN
RWDTTFITPL GFSLPIITTI GNHEAGGWKS SRGSVQFYTS YLPFQLGLQN IAPNDRPLQH
SHTIGNETII IVMDSWVVDQ IPDQVSWMEQ VLSDNNNKTF KFALYHIALY PCTKISMDVE
ISSLAKEFWG PVFDKYNLTV GYENHYHLYK RSKQLVNGLE HPNGTLYIGD GSWGVETTMK
LRDYDYLEVY GRIQHVIHSM VNSHNSTVNI ETINIDNEIF DSWERKLK
//
