ID Q86LF8_DROVI Unreviewed; 801 AA.
AC Q86LF8;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=Immunoglobulin-like cell adhesion protein {ECO:0000313|EMBL:AAO47838.1};
GN Name=kirre {ECO:0000313|EMBL:AAO47838.1};
OS Drosophila virilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7244 {ECO:0000313|EMBL:AAO47838.1};
RN [1] {ECO:0000313|EMBL:AAO47838.1}
RP NUCLEOTIDE SEQUENCE.
RA Struenkelnberg M., Hertenstein A., Fischbach K.-F.;
RL Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AAO47838.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12574866; DOI=10.1007/s00239-002-2393-2;
RA Strunkelnberg M., de Couet H.G., Hertenstein A., Fischbach K.F.;
RT "Interspecies comparison of a gene pair with partially redundant function:
RT the rst and kirre genes in D. virilis and D. melanogaster.";
RL J. Mol. Evol. 56:187-197(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; AF419623; AAO47838.1; -; mRNA.
DR AlphaFoldDB; Q86LF8; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11640:SF153; IRREGULAR CHIASM C-ROUGHEST PROTEIN-RELATED; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..801
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004300386"
FT TRANSMEM 568..590
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 79..178
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 183..279
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 286..374
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 377..442
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 448..558
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 33..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 769..801
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 779..801
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 801 AA; 87369 MW; B5B0AA935C8AA994 CRC64;
MKLVRVSRGL LLLQLVHLLL LLVVLPDGIV AKSKNKNKSN QNTHYGDSGG GISSSSSSSS
DDNINNNNNK LKGHGEGGQH FAMEPQDQTA VVGSRVTLPC RVMGKVGALQ WTKDDFGLGQ
HRNLSGFERY SMVGSDEEGD FSLDIYPLML DDDAKYQCQV GPGPQGERGI RSRFANLTVL
VPPEAPKIQQ GDYLVTTEDR EIELECISAG GKPAAEITWI DGLGNVLTAE SFFEPMADSR
RINTKSVLKL APKKKYHNTT ITCQAQNTAD RTYRSAKVLL EVKYAPKVSV SVVGGALAGG
RIPEGAEVIL SCQADANPPE VSYRWFINDE LITGDFTTKM IIHNVTRKYH DAIVKCEVVN
AVGKSEESET LDISFGPVFR QRPVSKEADL GATVTMRCEV SGNPTPEIEW INENSDQEIV
GRAPELKLKV SSETAGRYFC KAVVNGFPEI GAEATVYVKR APIITSHKVQ FGAVGSRAKI
DCLAFSIPKA EHILWSFEGK LINMSSADPD IYIFEEHHLP EGVRAALIIK ESRSTHYGKY
NCTIINSYGG DSLIITLVPE PGSIPVPLVV MGSMSLVAIV LMVVMIVIVY RKRRRRKKPM
SADVIPEASR GGDKLNELKS ELRAKAYDVE YSEAGSDGLA INLTQTPMPD VQMKGATLGV
PLAGPVKFDE RFSGDYSDRY NRQCHIKNLK NQPDQAYKET TSNGYAPYFE YALDYSPPAD
SGKVKGAACG INSATLPHFA ANASGAAPNT AGGVPLSGGA SLPRNQRHEL HHNHQQHQHQ
QHQQQQQPKL PQTSQANGFL G
//
