ID Q87A58_XYLFT Unreviewed; 335 AA.
AC Q87A58;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 106.
DE SubName: Full=Isocitrate/isopropylmalate dehydrogenase {ECO:0000313|EMBL:AAO29802.1};
GN Name=icdA {ECO:0000313|EMBL:AAO29802.1};
GN OrderedLocusNames=PD_1973 {ECO:0000313|EMBL:AAO29802.1};
OS Xylella fastidiosa (strain Temecula1 / ATCC 700964).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xylella.
OX NCBI_TaxID=183190 {ECO:0000313|EMBL:AAO29802.1, ECO:0000313|Proteomes:UP000002516};
RN [1] {ECO:0000313|EMBL:AAO29802.1, ECO:0000313|Proteomes:UP000002516}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Temecula1 / ATCC 700964 {ECO:0000313|Proteomes:UP000002516};
RX PubMed=12533478; DOI=10.1128/JB.185.3.1018-1026.2003;
RA Van Sluys M.A., de Oliveira M.C., Monteiro-Vitorello C.B., Miyaki C.Y.,
RA Furlan L.R., Camargo L.E., da Silva A.C., Moon D.H., Takita M.A.,
RA Lemos E.G., Machado M.A., Ferro M.I., da Silva F.R., Goldman M.H.,
RA Goldman G.H., Lemos M.V., El-Dorry H., Tsai S.M., Carrer H., Carraro D.M.,
RA de Oliveira R.C., Nunes L.R., Siqueira W.J., Coutinho L.L., Kimura E.T.,
RA Ferro E.S., Harakava R., Kuramae E.E., Marino C.L., Giglioti E.,
RA Abreu I.L., Alves L.M., do Amaral A.M., Baia G.S., Blanco S.R., Brito M.S.,
RA Cannavan F.S., Celestino A.V., da Cunha A.F., Fenille R.C., Ferro J.A.,
RA Formighieri E.F., Kishi L.T., Leoni S.G., Oliveira A.R., Rosa V.E.Jr.,
RA Sassaki F.T., Sena J.A., de Souza A.A., Truffi D., Tsukumo F., Yanai G.M.,
RA Zaros L.G., Civerolo E.L., Simpson A.J., Almeida N.F.Jr., Setubal J.C.,
RA Kitajima J.P.;
RT "Comparative analyses of the complete genome sequences of Pierce's disease
RT and citrus variegated chlorosis strains of Xylella fastidiosa.";
RL J. Bacteriol. 185:1018-1026(2003).
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
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DR EMBL; AE009442; AAO29802.1; -; Genomic_DNA.
DR RefSeq; WP_004087529.1; NC_004556.1.
DR AlphaFoldDB; Q87A58; -.
DR GeneID; 58017492; -.
DR KEGG; xft:PD_1973; -.
DR HOGENOM; CLU_031953_0_1_6; -.
DR Proteomes; UP000002516; Chromosome.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR PANTHER; PTHR11835:SF34; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR PROSITE; PS00470; IDH_IMDH; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002516}.
FT DOMAIN 4..331
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
SQ SEQUENCE 335 AA; 35704 MW; 4A3BB291EC1B1971 CRC64;
MTQTITVIRG DGIGPEIMDA TLSVLNALQA NLNYEFADAG LSALEKHGDL LPESTLNSIS
KNKIALKSPL TTPVGEGFSS INVALRRKFD LYANVRPAKS FPNTKSRFSD NVDLITVREN
TEGAYLSEGQ TISPDGEVAT SSARVTRKGS ERIVRYAFDL ARTTGRKKVT AVHKANIIKS
TSGLFLKTAR DVASQYPEID FQEMIVDNTC MQLVMRPEQF DIIVTTNLFG DILSDLCAGL
VGGLGLAPGA NIGNEQAIFE AVHGSAPDIA GQGKANPCAL LLGAVQMLDH IGQPQNAERL
RNAIVATLNA KDSLTPDLGG NGNTMGFAKA IASRL
//
