ID Q87I43_VIBPA Unreviewed; 524 AA.
AC Q87I43;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE SubName: Full=Putative sensor kinase CitA {ECO:0000313|EMBL:BAC62106.1};
GN OrderedLocusNames=VPA0763 {ECO:0000313|EMBL:BAC62106.1};
OS Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=223926 {ECO:0000313|EMBL:BAC62106.1, ECO:0000313|Proteomes:UP000002493};
RN [1] {ECO:0000313|EMBL:BAC62106.1, ECO:0000313|Proteomes:UP000002493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RIMD 2210633 {ECO:0000313|Proteomes:UP000002493};
RX PubMed=12620739; DOI=10.1016/S0140-6736(03)12659-1;
RA Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT distinct from that of V. cholerae.";
RL Lancet 361:743-749(2003).
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DR EMBL; BA000032; BAC62106.1; -; Genomic_DNA.
DR RefSeq; NP_800273.1; NC_004605.1.
DR RefSeq; WP_005481283.1; NC_004605.1.
DR AlphaFoldDB; Q87I43; -.
DR GeneID; 1191452; -.
DR KEGG; vpa:VPA0763; -.
DR PATRIC; fig|223926.6.peg.3696; -.
DR eggNOG; COG3290; Bacteria.
DR HOGENOM; CLU_020211_11_2_6; -.
DR Proteomes; UP000002493; Chromosome 2.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR032834; NatK_C.
DR InterPro; IPR033463; sCache_3.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR039506; SPOB_a.
DR PANTHER; PTHR40448; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR40448:SF1; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF14501; HATPase_c_5; 1.
DR Pfam; PF17203; sCache_3_2; 1.
DR Pfam; PF14689; SPOB_a; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:BAC62106.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002493};
KW Transferase {ECO:0000313|EMBL:BAC62106.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 331..523
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 524 AA; 57307 MW; 390198F288F18177 CRC64;
MPFASFSFTK QLAVLLSGVM LLGMLSWWSY SAHQLDDILT HQISLRAQVQ SQQLSQLSSL
IAAVGSGSAS KTSEIINAVQ AVSDADFITV SDRAGIRLAH PVAERVGLPV LGGDIERALE
NGESYLSYGV GSLGPSVRYI SPIFSNEGDV IGMIKVGYLI DTLDLWTSER LLPLISFGII
AVAICIWLSW KFSRYVRTQM QELEPWQLKQ ALKTHQGVLQ ATYEGLVAIN SEGSLYLIND
SARAMLNYHQ ELGNVFTDGI DNPESFSLKG DDYINGLIRV NGKNLVMNRV TLRTSTGEPY
GAVFSLRDQN EMHVLSEKIS QVTQYMENMR VARHEYQNKL STISGLLQMG AYDKALSVCL
SQAKASQSQL DSLHALNSRP ALSALILAKA SKANELGVAL SIDCQSDLSA LSRRLSEEQL
CGLIGNLAQN ALEAVKGQEN GHVHIGISES ACEYTIQVSN NGPLLESEFD VLCELGFTTK
QNKADHGVGM YLVRSIVEQG NGHMELDSDE QETAFTIYFP KELG
//
