ID Q87MH2_VIBPA Unreviewed; 417 AA.
AC Q87MH2;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE SubName: Full=Uracil permease {ECO:0000313|EMBL:BAC60546.1};
GN OrderedLocusNames=VP2283 {ECO:0000313|EMBL:BAC60546.1};
OS Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=223926 {ECO:0000313|EMBL:BAC60546.1, ECO:0000313|Proteomes:UP000002493};
RN [1] {ECO:0000313|EMBL:BAC60546.1, ECO:0000313|Proteomes:UP000002493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RIMD 2210633 {ECO:0000313|Proteomes:UP000002493};
RX PubMed=12620739; DOI=10.1016/S0140-6736(03)12659-1;
RA Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT distinct from that of V. cholerae.";
RL Lancet 361:743-749(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; BA000031; BAC60546.1; -; Genomic_DNA.
DR RefSeq; NP_798662.1; NC_004603.1.
DR RefSeq; WP_005457676.1; NC_004603.1.
DR AlphaFoldDB; Q87MH2; -.
DR GeneID; 1189796; -.
DR KEGG; vpa:VP2283; -.
DR PATRIC; fig|223926.6.peg.2185; -.
DR eggNOG; COG2233; Bacteria.
DR HOGENOM; CLU_017959_1_2_6; -.
DR Proteomes; UP000002493; Chromosome 1.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002493};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 417 AA; 42962 MW; C25CD31377A85D94 CRC64;
MKNALQGAQM LFVAFGALVL VPLLTGLDPN VALFGAGVGT LLFQLITKRS VPIFLASSFA
FIAPIMFGIQ TWGIGATMGG LMAAGLVYVA LGAMIKVRGV GFIHKILPPV VVGPVIMVIG
LGLAPTAVNM AVGKTGDGAV QLVNGDAAVI ISAVSLLTTI ALSVFAKGFL KLVPIVGGIL
AGYSVSLFYG VVDFTPVAQA AWLAMPNFTM PEFNINAILF MIPVAIAPAV EHVGDMLAIS
NVTGKNYLKK PGLHRTIAGD GIATIAASMV GAPPNTTYSE VTGAVMLTKA FNPVIMTWAA
ITAIVLALVG KLGAILQTIP VPVMGGIMIL LFGSIATVGL NTLIKNNVDL HKSRNLVIVA
VTLVFGIGGM AFGIGEFSLQ GVSLCGIVAI LLNLVLPHDL GENHVVDNAQ MEEESAK
//
