ID Q87TN0_VIBPA Unreviewed; 368 AA.
AC Q87TN0;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE RecName: Full=RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein {ECO:0000259|Pfam:PF16576};
GN OrderedLocusNames=VP0039 {ECO:0000313|EMBL:BAC58302.1};
OS Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=223926 {ECO:0000313|EMBL:BAC58302.1, ECO:0000313|Proteomes:UP000002493};
RN [1] {ECO:0000313|EMBL:BAC58302.1, ECO:0000313|Proteomes:UP000002493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RIMD 2210633 {ECO:0000313|Proteomes:UP000002493};
RX PubMed=12620739; DOI=10.1016/S0140-6736(03)12659-1;
RA Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT distinct from that of V. cholerae.";
RL Lancet 361:743-749(2003).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BA000031; BAC58302.1; -; Genomic_DNA.
DR RefSeq; NP_796418.1; NC_004603.1.
DR RefSeq; WP_005455175.1; NC_004603.1.
DR AlphaFoldDB; Q87TN0; -.
DR GeneID; 1187501; -.
DR KEGG; vpa:VP0039; -.
DR PATRIC; fig|223926.6.peg.38; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_1_2_6; -.
DR Proteomes; UP000002493; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF11; BLL4320 PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002493}.
FT DOMAIN 61..269
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 368 AA; 40446 MW; 08D8D66CCBDE2DE9 CRC64;
MKKWTFFMLL IAVLLFGSVI GFNLFKQQKI AEYMANRPEP EFPVTVTEVK AVDWVPVIEA
IGFIEPNQGV TVANETSGVI DKIAFESGTQ VEAGQPLVLL DSEVEKANLK SSQAKLPAAE
AKYKRYQGLF KKGSISKEAY DEAEANYYSL KADIESLKAT IDRREIKAPF AGVVGIRNVY
LGQYIQAGSD IVRLEDSSVM RLRFTVPQTD ISRIKLDQEV DIFVDAYPDQ PFKGSISAIE
PAVNVQSGLI QVQADIPNSD GKLRSGMFAR ANIIMPKLAN QVTLPQTAIT FTLYGDNVYI
VTEEEGEKRV KQHVVKVGER TKDIAHILAG VKPGDVVVTS GQVRLSNHAK VSIVESNAIT
PPAETPML
//
