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Database: UniProt
Entry: Q883Y4
LinkDB: Q883Y4
Original site: Q883Y4 
ID   GPDA_PSESM              Reviewed;         341 AA.
AC   Q883Y4;
DT   31-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   09-JUL-2014, entry version 90.
DE   RecName: Full=Glycerol-3-phosphate dehydrogenase [NAD(P)+];
DE            EC=1.1.1.94;
DE   AltName: Full=NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;
GN   Name=gpsA; OrderedLocusNames=PSPTO_2213;
OS   Pseudomonas syringae pv. tomato (strain DC3000).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=223283;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DC3000;
RX   PubMed=12928499; DOI=10.1073/pnas.1731982100;
RA   Buell C.R., Joardar V., Lindeberg M., Selengut J., Paulsen I.T.,
RA   Gwinn M.L., Dodson R.J., DeBoy R.T., Durkin A.S., Kolonay J.F.,
RA   Madupu R., Daugherty S.C., Brinkac L.M., Beanan M.J., Haft D.H.,
RA   Nelson W.C., Davidsen T.M., Zafar N., Zhou L., Liu J., Yuan Q.,
RA   Khouri H.M., Fedorova N.B., Tran B., Russell D., Berry K.J.,
RA   Utterback T.R., Van Aken S.E., Feldblyum T.V., D'Ascenzo M.,
RA   Deng W.-L., Ramos A.R., Alfano J.R., Cartinhour S., Chatterjee A.K.,
RA   Delaney T.P., Lazarowitz S.G., Martin G.B., Schneider D.J., Tang X.,
RA   Bender C.L., White O., Fraser C.M., Collmer A.;
RT   "The complete genome sequence of the Arabidopsis and tomato pathogen
RT   Pseudomonas syringae pv. tomato DC3000.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:10181-10186(2003).
CC   -!- CATALYTIC ACTIVITY: sn-glycerol 3-phosphate + NAD(P)(+) =
CC       glycerone phosphate + NAD(P)H.
CC   -!- PATHWAY: Membrane lipid metabolism; glycerophospholipid
CC       metabolism.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the NAD-dependent glycerol-3-phosphate
CC       dehydrogenase family.
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DR   EMBL; AE016853; AAO55729.1; -; Genomic_DNA.
DR   RefSeq; NP_792034.1; NC_004578.1.
DR   ProteinModelPortal; Q883Y4; -.
DR   STRING; 223283.PSPTO_2213; -.
DR   EnsemblBacteria; AAO55729; AAO55729; PSPTO_2213.
DR   GeneID; 1183864; -.
DR   KEGG; pst:PSPTO_2213; -.
DR   PATRIC; 19995714; VBIPseSyr93040_2245.
DR   eggNOG; COG0240; -.
DR   HOGENOM; HOG000246853; -.
DR   KO; K00057; -.
DR   OMA; MPISTAV; -.
DR   OrthoDB; EOG6JDWF4; -.
DR   PhylomeDB; Q883Y4; -.
DR   BioCyc; PSYR223283:GJIX-2258-MONOMER; -.
DR   UniPathway; UPA00940; -.
DR   GO; GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; IEA:InterPro.
DR   GO; GO:0047952; F:glycerol-3-phosphate dehydrogenase [NAD(P)+] activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0004367; F:glycerol-3-phosphate dehydrogenase [NAD+] activity; IEA:UniProtKB-EC.
DR   GO; GO:0036439; F:glycerol-3-phosphate dehydrogenase [NADP+] activity; IEA:UniProtKB-EC.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0046167; P:glycerol-3-phosphate biosynthetic process; IEA:UniProtKB-HAMAP.
DR   GO; GO:0046168; P:glycerol-3-phosphate catabolic process; IEA:InterPro.
DR   GO; GO:0006650; P:glycerophospholipid metabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-HAMAP.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   Gene3D; 3.40.50.720; -; 1.
DR   HAMAP; MF_00394; NAD_Glyc3P_dehydrog; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH_C-like.
DR   InterPro; IPR013328; DH_multihelical.
DR   InterPro; IPR006168; G3P_DH_NAD-dep.
DR   InterPro; IPR006109; G3P_DH_NAD-dep_C.
DR   InterPro; IPR011128; G3P_DH_NAD-dep_N.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   PANTHER; PTHR11728; PTHR11728; 1.
DR   Pfam; PF07479; NAD_Gly3P_dh_C; 1.
DR   Pfam; PF01210; NAD_Gly3P_dh_N; 1.
DR   PIRSF; PIRSF000114; Glycerol-3-P_dh; 1.
DR   PRINTS; PR00077; GPDHDRGNASE.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   PROSITE; PS00957; NAD_G3PDH; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Lipid biosynthesis; Lipid metabolism;
KW   NAD; Oxidoreductase; Phospholipid biosynthesis;
KW   Phospholipid metabolism.
FT   CHAIN         1    341       Glycerol-3-phosphate dehydrogenase
FT                                [NAD(P)+].
FT                                /FTId=PRO_0000138011.
FT   NP_BIND      11     16       NAD (By similarity).
FT   REGION      255    256       Substrate binding (By similarity).
FT   ACT_SITE    191    191       Proton acceptor (By similarity).
FT   BINDING     108    108       NAD; via amide nitrogen (By similarity).
FT   BINDING     108    108       Substrate (By similarity).
FT   BINDING     140    140       NAD; via amide nitrogen (By similarity).
FT   BINDING     255    255       NAD (By similarity).
FT   BINDING     281    281       NAD (By similarity).
SQ   SEQUENCE   341 AA;  36680 MW;  DEDE1DE7BBE7F1A0 CRC64;
     MTTQQPVAVL GGGSFGTAIA NLLAENGHQV RQWMRDPEQA EAIRVNRENP RYLKGIKVRP
     EVEPVTDLTA ALEVSELIFV ALPSSALRSV LSPHIERLSG KMLVSLTKGI EAQSFKLMSQ
     ILEEIVPQAR IGVLSGPNLA REIAEHALTA TVVASEDEDL CQQVQAALHG RTFRVYASND
     RFGVELGGAL KNVYAIIAGM AVALDMGENT KSMLITRALA EMTRFAVSQG ANPMTFLGLA
     GVGDLIVTCS SPKSRNYQVG FALGQGLSLE EAVTRLGEVA EGVNTLKVLK VKAQEVQVYM
     PLVAGLHAIL FEGRTLSQVI EALMRAEPKT DVDFISITGF N
//
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