ID Q88D78_PSEPK Unreviewed; 480 AA.
AC Q88D78;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 2.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Peptidase, TldD/PmbA family {ECO:0000313|EMBL:AAN70516.2};
GN OrderedLocusNames=PP_4949 {ECO:0000313|EMBL:AAN70516.2};
OS Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950
OS / KT2440).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=160488 {ECO:0000313|EMBL:AAN70516.2, ECO:0000313|Proteomes:UP000000556};
RN [1] {ECO:0000313|EMBL:AAN70516.2, ECO:0000313|Proteomes:UP000000556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440
RC {ECO:0000313|Proteomes:UP000000556};
RX PubMed=12534463; DOI=10.1046/j.1462-2920.2002.00366.x;
RA Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H.,
RA Martins dos Santos V.A., Fouts D.E., Gill S.R., Pop M., Holmes M.,
RA Brinkac L., Beanan M., DeBoy R.T., Daugherty S., Kolonay J., Madupu R.,
RA Nelson W., White O., Peterson J., Khouri H., Hance I., Chris Lee P.,
RA Holtzapple E., Scanlan D., Tran K., Moazzez A., Utterback T., Rizzo M.,
RA Lee K., Kosack D., Moestl D., Wedler H., Lauber J., Stjepandic D.,
RA Hoheisel J., Straetz M., Heim S., Kiewitz C., Eisen J.A., Timmis K.N.,
RA Dusterhoft A., Tummler B., Fraser C.M.;
RT "Complete genome sequence and comparative analysis of the metabolically
RT versatile Pseudomonas putida KT2440.";
RL Environ. Microbiol. 4:799-808(2002).
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
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DR EMBL; AE015451; AAN70516.2; -; Genomic_DNA.
DR RefSeq; NP_747052.2; NC_002947.4.
DR RefSeq; WP_049587479.1; NC_002947.4.
DR AlphaFoldDB; Q88D78; -.
DR STRING; 160488.PP_4949; -.
DR PaxDb; 160488-PP_4949; -.
DR GeneID; 83682683; -.
DR KEGG; ppu:PP_4949; -.
DR PATRIC; fig|160488.4.peg.5285; -.
DR eggNOG; COG0312; Bacteria.
DR OrthoDB; 9803213at2; -.
DR BioCyc; PPUT160488:G1G01-5293-MONOMER; -.
DR Proteomes; UP000000556; Chromosome.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR30624:SF10; CONSERVED PROTEIN; 1.
DR PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000000556}.
FT DOMAIN 24..86
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 127..225
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 236..475
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 480 AA; 52198 MW; 7B9D39378C07E48E CRC64;
MFDSSALLRQ RFAALRSTAE LFSLRHVKQS HQALSVRRNV AEPPFFSQDE GAMLTVRVNG
VEAYAATADL SQAGLQRALE QAEALARQIA RHSLLDLREH AVTSARHDHV SPNFDQPVPS
LADCLGLLAA ESASVPKDSR LVDWQASLGL SLVEQTYLNS AGAELRHAQR FLFPGLGVTA
SDGQDSQSRS LGRDNFGQQG GFEIIERCGL VGAASRVAEE ALQLLLAPNT PSGPRDLLLM
PDQMMLQIHE SIGHPLEMDR ILGDERNYAG TSFVKTSDFG HLQYGSSLLN VTFDPTIGEE
LASYSHDDDG TPASKAFLIR DGLLLRPLGG ALSQFRSGLD GVANSRACGW NRAPIDRMAN
LNIEPGDQSF EQLIGGIEHG ILMRTNRSWS IDDARNKFQF GCEWGQLIEN GELKGIVKNP
NYRGISAQFW RNLSAVGDHS TFQVLGTPNC GKGEPNQVVR VGHASPACVF RQIDVFGGDA
//
