ID Q898M5_CLOTE Unreviewed; 380 AA.
AC Q898M5;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 109.
DE SubName: Full=Methyltransferase {ECO:0000313|EMBL:AAO35054.1};
DE EC=2.1.1.- {ECO:0000313|EMBL:AAO35054.1};
GN OrderedLocusNames=CTC_00420 {ECO:0000313|EMBL:AAO35054.1};
OS Clostridium tetani (strain Massachusetts / E88).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=212717 {ECO:0000313|EMBL:AAO35054.1, ECO:0000313|Proteomes:UP000001412};
RN [1] {ECO:0000313|EMBL:AAO35054.1, ECO:0000313|Proteomes:UP000001412}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Massachusetts / E88 {ECO:0000313|Proteomes:UP000001412};
RX PubMed=12552129; DOI=10.1073/pnas.0335853100;
RA Brueggemann H., Baumer S., Fricke W.F., Wiezer A., Liesegang H., Decker I.,
RA Herzberg C., Martinez-Arias R., Merkl R., Henne A., Gottschalk G.;
RT "The genome sequence of Clostridium tetani, the causative agent of tetanus
RT disease.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:1316-1321(2003).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE015927; AAO35054.1; -; Genomic_DNA.
DR RefSeq; WP_011098725.1; NC_004557.1.
DR AlphaFoldDB; Q898M5; -.
DR STRING; 212717.CTC_00420; -.
DR GeneID; 24252966; -.
DR KEGG; ctc:CTC_00420; -.
DR HOGENOM; CLU_032119_3_1_9; -.
DR OrthoDB; 9809404at2; -.
DR Proteomes; UP000001412; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS01261; UPF0020; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:AAO35054.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001412};
KW Transferase {ECO:0000313|EMBL:AAO35054.1}.
FT DOMAIN 195..206
FT /note="UPF0020"
FT /evidence="ECO:0000259|PROSITE:PS01261"
SQ SEQUENCE 380 AA; 43636 MW; 8F6D53D2ECECC3C8 CRC64;
MDYTLIATAT FGLEKVVADE LRELGYEDLI IENGKVTFQG SEMDIVTCNM WLRTADRVLI
KMAEFKAESF EELFQGTLKV EWGDIIPETG FMHVTGKSVK SKLFSVPDCQ SITKKAVVES
MKRKYNKEMF SEDGATYKIE VAILKDIVTL TLDTTGPGLH KRGYREFAGE APLKETLAAA
LVLLSKWEPS RILADPFCGS GTIPIEAAMI GKNIAPGLNR NFVSEDWDII PKNLWQDMRK
YARNSINDKE FRILASDING RVLKTARDNA EKAGVADYIA FQRMDMKEFR NKKRYGFIIT
NPPYGERIGN AKEVENLYED MGRTFQELKD WSYFVITSYE DFENCFGEKS DKNRKLYNGR
IKCYYYQYFG AEPEKNPWEK
//
