ID Q89YK5_BACTN Unreviewed; 843 AA.
AC Q89YK5;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 08-NOV-2023, entry version 108.
DE SubName: Full=Glycerophosphoryl diester phosphodiesterase {ECO:0000313|EMBL:AAO79831.1};
GN OrderedLocusNames=BT_4726 {ECO:0000313|EMBL:AAO79831.1};
OS Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 /
OS CCUG 10774 / NCTC 10582 / VPI-5482 / E50).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=226186 {ECO:0000313|EMBL:AAO79831.1, ECO:0000313|Proteomes:UP000001414};
RN [1] {ECO:0000313|EMBL:AAO79831.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=12663928; DOI=10.1126/science.1080029;
RA Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C.,
RA Hooper L.V., Gordon J.I.;
RT "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
RL Science 299:2074-2076(2003).
RN [2] {ECO:0000313|EMBL:AAO79831.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=19321416; DOI=10.1073/pnas.0901529106;
RA Mahowald M.A., Rey F.E., Seedorf H., Turnbaugh P.J., Fulton R.S.,
RA Wollam A., Shah N., Wang C., Magrini V., Wilson R.K., Cantarel B.L.,
RA Coutinho P.M., Henrissat B., Crock L.W., Russell A., Verberkmoes N.C.,
RA Hettich R.L., Gordon J.I.;
RT "Characterizing a model human gut microbiota composed of members of its two
RT dominant bacterial phyla.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5859-5864(2009).
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DR EMBL; AE015928; AAO79831.1; -; Genomic_DNA.
DR RefSeq; NP_813637.1; NC_004663.1.
DR RefSeq; WP_008766762.1; NC_004663.1.
DR AlphaFoldDB; Q89YK5; -.
DR STRING; 226186.BT_4726; -.
DR PaxDb; 226186-BT_4726; -.
DR EnsemblBacteria; AAO79831; AAO79831; BT_4726.
DR GeneID; 60925898; -.
DR KEGG; bth:BT_4726; -.
DR PATRIC; fig|226186.12.peg.4805; -.
DR eggNOG; COG0584; Bacteria.
DR eggNOG; COG1520; Bacteria.
DR eggNOG; COG3291; Bacteria.
DR HOGENOM; CLU_337620_0_0_10; -.
DR InParanoid; Q89YK5; -.
DR OrthoDB; 1491323at2; -.
DR Proteomes; UP000001414; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IBA:GO_Central.
DR GO; GO:0006580; P:ethanolamine metabolic process; IBA:GO_Central.
DR GO; GO:0070291; P:N-acylethanolamine metabolic process; IBA:GO_Central.
DR GO; GO:0006644; P:phospholipid metabolic process; IBA:GO_Central.
DR CDD; cd08566; GDPD_AtGDE_like; 1.
DR CDD; cd00146; PKD; 1.
DR Gene3D; 2.40.10.480; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR InterPro; IPR002372; PQQ_repeat.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR PANTHER; PTHR46320; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1; 1.
DR PANTHER; PTHR46320:SF1; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1; 1.
DR Pfam; PF03009; GDPD; 1.
DR Pfam; PF18911; PKD_4; 1.
DR Pfam; PF13360; PQQ_2; 1.
DR SMART; SM00089; PKD; 1.
DR SMART; SM00564; PQQ; 2.
DR SUPFAM; SSF49299; PKD domain; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS51704; GP_PDE; 1.
DR PROSITE; PS50093; PKD; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001414};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..843
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004302721"
FT DOMAIN 42..108
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 590..837
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
FT REGION 537..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 843 AA; 89492 MW; A7C6BB4EDD609346 CRC64;
MKNIKIFATF CICLLLFSAC SDDWKENALT AKFSFDKSLY YVGDEVRITN ETVGGEGNYT
YEWDLGDGKT STDPNPVVTY QTNGAYTVTL HVKDAKGTYA MAHKLLTIDS EPLPEVGNVK
LKWVGGHVLG EVRSTAPAVS DDNGVYMTSN DHYLRKFSAA TGDQLWEFDL WTSADGDAPS
GNTHTTPSID IDGTIYVGTG DTSGKVGRVY AINPDGSKKW LVAGDAEKGF WNKGNASTPR
INYLTCAIGE NHVYMGNGGS TGSVLAVDKV TGYRVGYVAN ADNSGGPSGG VSAGIVLANN
TLVWGGGKNG LFGASASALN AGGNVMWAWQ VFSSGDDKPS ENMNGSPAVD EAGTIYGTAT
FAGMGSSAFA MGSDGVEKWR TPLGNVGTLD QGGVVIGLDG SIIVTVKRAP GEATGGIISL
SPGGAIQWHY GIAEDVSGCA AIDQAGNIHF GTQSGNYYII KPEESDEQLI LKKDLAALIS
ESDSPLKGDW EAGIGKIWSS PTIGPDGAIY IGVTNTVDPT KSVLVALEDE GITGAATSAW
PMKGKDRRHS GAQSGGNGEN PGGEEGGQLP MTGNLKADLK SLFESTSYKV WLCAHRGNTQ
KGMKEGIPEN SLPAIEHSVK AGVEMIELDA RPTSDGVLVL MHDNTIDRTT NGSGAVGDFT
YQQLQQFYLK DASGNITGER IPTLEEAMKK GKGKVYYNLD IVNKNVAVNT IVALLKKLDM
EGSTLLYVSN NRNYAFDLKT ANSSLLLHPM AKAADDITYF SSSYTDNVQM MQLSTSDAMG
GTMVNEIKDQ GWLLFSNIVG ANDTNMLSEN YSGLVGMINK RINIVQTDYA EVAAKYLKSK
GYR
//
