ID Q8A2K1_BACTN Unreviewed; 356 AA.
AC Q8A2K1;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 113.
DE SubName: Full=Possible protein-tyrosine-phosphatase {ECO:0000313|EMBL:AAO78410.1};
GN OrderedLocusNames=BT_3304 {ECO:0000313|EMBL:AAO78410.1};
OS Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 /
OS CCUG 10774 / NCTC 10582 / VPI-5482 / E50).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=226186 {ECO:0000313|EMBL:AAO78410.1, ECO:0000313|Proteomes:UP000001414};
RN [1] {ECO:0000313|EMBL:AAO78410.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=12663928; DOI=10.1126/science.1080029;
RA Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C.,
RA Hooper L.V., Gordon J.I.;
RT "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
RL Science 299:2074-2076(2003).
RN [2] {ECO:0000313|EMBL:AAO78410.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=19321416; DOI=10.1073/pnas.0901529106;
RA Mahowald M.A., Rey F.E., Seedorf H., Turnbaugh P.J., Fulton R.S.,
RA Wollam A., Shah N., Wang C., Magrini V., Wilson R.K., Cantarel B.L.,
RA Coutinho P.M., Henrissat B., Crock L.W., Russell A., Verberkmoes N.C.,
RA Hettich R.L., Gordon J.I.;
RT "Characterizing a model human gut microbiota composed of members of its two
RT dominant bacterial phyla.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5859-5864(2009).
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DR EMBL; AE015928; AAO78410.1; -; Genomic_DNA.
DR RefSeq; NP_812216.1; NC_004663.1.
DR RefSeq; WP_011108754.1; NC_004663.1.
DR AlphaFoldDB; Q8A2K1; -.
DR SMR; Q8A2K1; -.
DR STRING; 226186.BT_3304; -.
DR PaxDb; 226186-BT_3304; -.
DR DNASU; 1072727; -.
DR EnsemblBacteria; AAO78410; AAO78410; BT_3304.
DR GeneID; 60924484; -.
DR KEGG; bth:BT_3304; -.
DR PATRIC; fig|226186.12.peg.3371; -.
DR eggNOG; COG2365; Bacteria.
DR HOGENOM; CLU_057546_0_1_10; -.
DR InParanoid; Q8A2K1; -.
DR OrthoDB; 1188001at2; -.
DR Proteomes; UP000001414; Chromosome.
DR GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd14529; TpbA-like; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR026893; Tyr/Ser_Pase_IphP-type.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR31126:SF1; PTP_DSP-LIKE; 1.
DR PANTHER; PTHR31126; TYROSINE-PROTEIN PHOSPHATASE; 1.
DR Pfam; PF13350; Y_phosphatase3; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001414};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..356
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004302776"
FT DOMAIN 223..278
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
SQ SEQUENCE 356 AA; 40719 MW; ABF28A0AA9A9012B CRC64;
MYRNLLNWLT ILLVFPSCSG TSPTISVVCE ENNVGNAIIK WETAPILKGQ VKVYASTSPD
FIPEENPVVT INIAKGKKTI VTNDPSQRYY YLMVFNNRYR VRVAARNVNI PGIQNFRDLG
GYKSAETGKD TRWGMLYRSA QIDSIPFCSR RELKNMGIRT IIDLRSEEER HNYPQLHDED
FNVLHLPIAT GNMEHILQDI RDKKIETDTI YRLVERMNRQ LVTNYRKEYK ELFTLLLDRN
NYPVVIHCTS GKGRTGIVSA LVLAALGVNE EAIMKDYRLS NDYFNIPKAS RYAYKLPINS
QEAITTIYSA KEDFLNAAKE QIDAEYGSVQ AYLKKGIGLS AEEIERLRSI LLIDNG
//
