ID Q8A8A0_BACTN Unreviewed; 434 AA.
AC Q8A8A0;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=Outer membrane protein {ECO:0000313|EMBL:AAO76374.1};
GN OrderedLocusNames=BT_1267 {ECO:0000313|EMBL:AAO76374.1};
OS Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 /
OS CCUG 10774 / NCTC 10582 / VPI-5482 / E50).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=226186 {ECO:0000313|EMBL:AAO76374.1, ECO:0000313|Proteomes:UP000001414};
RN [1] {ECO:0000313|EMBL:AAO76374.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=12663928; DOI=10.1126/science.1080029;
RA Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C.,
RA Hooper L.V., Gordon J.I.;
RT "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
RL Science 299:2074-2076(2003).
RN [2] {ECO:0000313|EMBL:AAO76374.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=19321416; DOI=10.1073/pnas.0901529106;
RA Mahowald M.A., Rey F.E., Seedorf H., Turnbaugh P.J., Fulton R.S.,
RA Wollam A., Shah N., Wang C., Magrini V., Wilson R.K., Cantarel B.L.,
RA Coutinho P.M., Henrissat B., Crock L.W., Russell A., Verberkmoes N.C.,
RA Hettich R.L., Gordon J.I.;
RT "Characterizing a model human gut microbiota composed of members of its two
RT dominant bacterial phyla.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5859-5864(2009).
CC -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC family. {ECO:0000256|ARBA:ARBA00007613}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE015928; AAO76374.1; -; Genomic_DNA.
DR RefSeq; NP_810180.1; NC_004663.1.
DR RefSeq; WP_011107684.1; NC_004663.1.
DR AlphaFoldDB; Q8A8A0; -.
DR STRING; 226186.BT_1267; -.
DR PaxDb; 226186-BT_1267; -.
DR EnsemblBacteria; AAO76374; AAO76374; BT_1267.
DR GeneID; 60927243; -.
DR KEGG; bth:BT_1267; -.
DR PATRIC; fig|226186.12.peg.1293; -.
DR eggNOG; COG1538; Bacteria.
DR HOGENOM; CLU_012817_12_0_10; -.
DR InParanoid; Q8A8A0; -.
DR OrthoDB; 1046615at2; -.
DR Proteomes; UP000001414; Chromosome.
DR GO; GO:1990281; C:efflux pump complex; IBA:GO_Central.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015288; F:porin activity; IBA:GO_Central.
DR Gene3D; 1.20.1600.10; Outer membrane efflux proteins (OEP); 1.
DR InterPro; IPR003423; OMP_efflux.
DR PANTHER; PTHR30026; OUTER MEMBRANE PROTEIN TOLC; 1.
DR PANTHER; PTHR30026:SF21; SLR1270 PROTEIN; 1.
DR Pfam; PF02321; OEP; 2.
DR SUPFAM; SSF56954; Outer membrane efflux proteins (OEP); 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001414};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..434
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004303017"
FT COILED 344..385
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 434 AA; 48508 MW; 78A7763F5D3671FC CRC64;
MKIRIYSLLL CGFALGSLSA LAQQSPLLEK YRTMALDYNH DLKAAEKNIA ASMEVEKSAR
ADLKPKLSGT ANFQYTENPL ELTLDVPSLG LSRTVEGKQL NYGGSLSILQ PVYTGGRVLE
SIRMAQHQQS FAANQAKALN DAVCYQTDIQ YWSAVARQEI VTVAEDFRNS IAALVKTIKE
RVEVGLVDPQ DLLMAEVKLN EAEYQLLQAQ SNFETGRMAL NSMIGVRLEH HTELDSQIPV
VVVDDSTWLS TGMARPEIQM AYDRIRMAES TKKLNDSQFK PQFYVGIDGS YSSPGYNFKK
DLDPNYAVYA KVSVPIFEWG KRKSEKRASS FRVGMAEDNL NKVMDQVELE IGVARKALSQ
AMERVRLSEN SLAKAEENEA KAIERYNEGK VSVVEVIDAQ TYRQTSQVNY VQAKAAAQGH
YSELIKALHG YDCR
//
