ID   Q8B4Z7_9CALI            Unreviewed;       138 AA.
AC   Q8B4Z7;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   24-JAN-2024, entry version 72.
DE   SubName: Full=RNA dependent RNA polymerase {ECO:0000313|EMBL:AAM95183.1};
DE   Flags: Fragment;
OS   Norwalk-like virus.
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
OX   NCBI_TaxID=95340 {ECO:0000313|EMBL:AAM95183.1};
RN   [1] {ECO:0000313|EMBL:AAM95183.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Bo/Shrewsbury54/00/UK {ECO:0000313|EMBL:AAM95183.1};
RX   PubMed=12552024; DOI=10.1128/JVI.77.4.2789-2798.2003;
RA   Oliver S.L., Dastjerdi A.M., Wong S., El-Attar L., Gallimore C.,
RA   Brown D.W., Green J., Bridger J.C.;
RT   "Molecular characterization of bovine enteric caliciviruses: a distinct
RT   third genogroup of noroviruses (Norwalk-like viruses) unlikely to be of
RT   risk to humans.";
RL   J. Virol. 77:2789-2798(2003).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-
CC         diphosphate + H(+) + phosphate; Xref=Rhea:RHEA:23680,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:57930, ChEBI:CHEBI:61557; EC=3.6.1.15;
CC         Evidence={ECO:0000256|ARBA:ARBA00001491};
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DR   EMBL; AY126473; AAM95183.1; -; Genomic_RNA.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 1.20.960.20; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR004004; Helic/Pol/Pept_Calicivir-typ.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001205; RNA-dir_pol_C.
DR   Pfam; PF00680; RdRP_1; 1.
DR   PRINTS; PR00918; CALICVIRUSNS.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT   DOMAIN          4..137
FT                   /note="RNA-directed RNA polymerase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00680"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAM95183.1"
FT   NON_TER         138
FT                   /evidence="ECO:0000313|EMBL:AAM95183.1"
SQ   SEQUENCE   138 AA;  15697 MW;  63D784599BC1E9E6 CRC64;
     LTFCALSEVT NLDPDVVQAN SYFSFYGDDE IVSTDLEFDP DRLTKVLKGY GLKPTRPDKT
     EGPIELRRQV DGLVFLRRTI SHDAKGFQGR LDRESILRQL YWTRGPNHDD PNETLVPHSN
     RKVQLLCLLG EAALHGEK
//