ID   Q8CH70_MOUSE            Unreviewed;      1403 AA.
AC   Q8CH70;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   27-MAR-2024, entry version 113.
DE   SubName: Full=Baculoviral IAP repeat-containing 1e {ECO:0000313|EMBL:AAN77612.1};
GN   Name=Birc1e {ECO:0000313|EMBL:AAN77612.1};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|EMBL:AAN77612.1};
RN   [1] {ECO:0000313|EMBL:AAN77612.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=A/J {ECO:0000313|EMBL:AAN77612.1};
RX   PubMed=12526741; DOI=10.1016/S0960-9822(02)01359-3;
RA   Wright E.K., Goodart S.A., Growney J.D., Hadinoto V., Endrizzi M.G.,
RA   Long E.M., Sadigh K., Abney A.L., Bernstein-Hanley I., Dietrich W.F.;
RT   "Naip5 affects host susceptibility to the intracellular pathogen Legionella
RT   pneumophila.";
RL   Curr. Biol. 13:27-36(2003).
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DR   EMBL; AF367966; AAN77612.1; -; Genomic_DNA.
DR   MEROPS; I32.001; -.
DR   ChiTaRS; Naip5; mouse.
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IEA:InterPro.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   CDD; cd00022; BIR; 3.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001370; BIR_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR028789; Naip.
DR   InterPro; IPR040535; NLRC4_HD.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR46914; BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR46914:SF1; BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00653; BIR; 3.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17889; NLRC4_HD; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SMART; SM00238; BIR; 3.
DR   SUPFAM; SSF57924; Inhibitor of apoptosis (IAP) repeat; 3.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS01282; BIR_REPEAT_1; 2.
DR   PROSITE; PS50143; BIR_REPEAT_2; 3.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
FT   DOMAIN          464..759
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   1403 AA;  159749 MW;  3237E1CE2EA406EF CRC64;
     MAEHGESSED RISEIDYEFL PELSALLGVD AFQVAKSQEE EEHKERMKMK KGFNSQMRSE
     AKRLKTFETY DTFRSWTPQE MAAAGFYHTG VRLGVQCFCC SLILFGNSLR KLPIERHKKL
     RPECEFLQGK DVGNIGKYDI RVKRPEKMLR GGKARYHEEE ARLESFEDWP FYAHGTSPRV
     LSAAGFVFTG KRDTVQCFSC GGSLGNWEEG DDPWKEHAKW FPKCEFLQSK KSSEEIAQYI
     QSYEGFVHVT GEHFVKSWVR RELPMVSAYC NDSVFANEEL RMDMFKDWPQ ESPVGVEALV
     RAGFFYTGKK DIVRCFSCGG CLEKWAEGDD PMEDHIKFFP ECVFLQTLKS SAEVIPTLQS
     QYALPEATET TRESNHGDAA AVHSTVVDLG RSEAQWFQEA RSLSEQLRDN YTKATFRHMN
     LPEVCSSLGT DHLLSCDVSI ISKHISQPVQ EALTIPEVFS NLNSVMCVEG EAGSGKTTFL
     KRIAFLWASG CCPLLNRFQL VFYLSLSSIT PGQELAKIIC AQLLGAGGCI SEACLSSIIQ
     QLQHQVLFLL DDYSGLASLP QALHTLITKN YLSRTCLLIA VHTNRVRDIR LYLGTSLEIQ
     EFPFYNTVSV LRKFFSHDII CVEKLIIYFI DNKDLQGVYK TPLFVATVCT DWIQNASAQD
     KFQDVTLFQS YMQYLSLKYK ATAEPLQATV SSCGQLALTG LFSSCFEFNS DDLAEAGVDE
     DEKLTTLLMS KFTAQRLRPV YRFLGPLFQE FLAAMRLTEL LSSDRQEDQD LGLYYLRQID
     SPLKAINSFN IFLYYVSSHS SSKAAPTVVS HLLQLVDEKE SLENMSENED YMKLHPQTFL
     WFQFVRGLWL VSPESSSSFV SEHLLRLALI FAYESNTVAE CSPFILQFLR GKTLALRVLN
     LQYFRDHPES LLLLRSLKVS INGNKMSSYV DYSFKTYFEN LQPPAIDEEY TSAFEHISEW
     RRNFAQDEEI IKNYENIRPR ALPDISEGYW KLSPKPCKIP KLEVQVNNTD AADQALLQVL
     MEVFSASQSI EFRLFNSSGF LESICPALEL SKASVTKCSM SRLELSRAEQ ELLLTLPALQ
     SLEVSETNQL PDQLFHNLHK FLGLKELCVR LDGKPDVLSV LPGEFPNLLH MEKLSIQTST
     ESDLSKLVKF IQNFPNLHVF HLKCDFLSNC ESLMAVLASC KKLREIEFSG RCFEAMTFVN
     ILPNFVSLKI LNLKDQQFPD KETSEKFAQA LGSLRNLEEL LIPTGDGIHQ VAKLIVRQCL
     QLPCLRVLTF HDILDNDSVI EIARAATSGG FQKLENLDIS MNHKITEEGY RNFFQALDNL
     PNLQELNICR NIPGRIQVQA TTVKALGQCV SRLPSLIRLH MLSWLLDEED MKVINDVKER
     HPQSKRLIIF WKLIVPFSPV ILE
//