ID Q8CVE8_LEPIN Unreviewed; 468 AA.
AC Q8CVE8;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 2.
DT 24-JAN-2024, entry version 77.
DE SubName: Full=Outer membrane efflux protein {ECO:0000313|EMBL:AAN49162.2};
GN OrderedLocusNames=LA_1963 {ECO:0000313|EMBL:AAN49162.2};
OS Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain
OS 56601).
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=189518 {ECO:0000313|EMBL:AAN49162.2, ECO:0000313|Proteomes:UP000001408};
RN [1] {ECO:0000313|EMBL:AAN49162.2, ECO:0000313|Proteomes:UP000001408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=56601 {ECO:0000313|EMBL:AAN49162.2,
RC ECO:0000313|Proteomes:UP000001408};
RX PubMed=12712204; DOI=10.1038/nature01597;
RA Ren S.X., Fu G., Jiang X.G., Zeng R., Miao Y.G., Xu H., Zhang Y.X.,
RA Xiong H., Lu G., Lu L.F., Jiang H.Q., Jia J., Tu Y.F., Jiang J.X., Gu W.Y.,
RA Zhang Y.Q., Cai Z., Sheng H.H., Yin H.F., Zhang Y., Zhu G.F., Wan M.,
RA Huang H.L., Qian Z., Wang S.Y., Ma W., Yao Z.J., Shen Y., Qiang B.Q.,
RA Xia Q.C., Guo X.K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.M.,
RA Shi M.H., Chen Z., Xu J.G., Zhao G.P.;
RT "Unique physiological and pathogenic features of Leptospira interrogans
RT revealed by whole-genome sequencing.";
RL Nature 422:888-893(2003).
CC -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC family. {ECO:0000256|ARBA:ARBA00007613}.
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DR EMBL; AE010300; AAN49162.2; -; Genomic_DNA.
DR RefSeq; NP_712144.2; NC_004342.2.
DR RefSeq; WP_000718042.1; NC_004342.2.
DR AlphaFoldDB; Q8CVE8; -.
DR STRING; 189518.LA_1963; -.
DR PaxDb; 189518-LA_1963; -.
DR EnsemblBacteria; AAN49162; AAN49162; LA_1963.
DR KEGG; lil:LA_1963; -.
DR PATRIC; fig|189518.3.peg.1956; -.
DR HOGENOM; CLU_012817_14_4_12; -.
DR InParanoid; Q8CVE8; -.
DR OrthoDB; 9791261at2; -.
DR Proteomes; UP000001408; Chromosome I.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1600.10; Outer membrane efflux proteins (OEP); 1.
DR InterPro; IPR003423; OMP_efflux.
DR PANTHER; PTHR30203; OUTER MEMBRANE CATION EFFLUX PROTEIN; 1.
DR PANTHER; PTHR30203:SF23; OUTER MEMBRANE EFFLUX PROTEIN; 1.
DR Pfam; PF02321; OEP; 2.
DR SUPFAM; SSF56954; Outer membrane efflux proteins (OEP); 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001408}.
FT COILED 350..377
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 468 AA; 54259 MW; EE2872196907DC86 CRC64;
MKKIFILLFF LVLTICVFSE ESKTEVLDSA IFPKENEESK NSLNWEEKPT FEKERVLDLK
TAEEKLWRNN LLLLASRFNI DARKAGIEQA GLYANPNIFI DQSIYAEPTQ RYFDFSRSGQ
TVVQIQQLFL LGGKIGKRVR VAELNARMSE QEFYDLARGL VTKLRKLFYA IYYYRQAISF
YDQSLEALGK TVSSAEMGYK RRAILQAEVL RLKALYFFLK KEREDLNIRI LEREADLRVL
LNDDSLKNPE TKIVPEIVEE NLDLLEPAKL KREELLEVAR NKRPDLKKAV QALRYEEANL
ELQHANAIPD LAFGPMYNRG GTAFQNYWGI TAQLNVPIFD RNQGNIKASE KAVLSRKQEL
KNTLLEVENE VAVSIETARV KDELYKKFKN TYTREYTDLS KDMILSYEKR YITILEFADF
FETYRSSIVE MLKLQTDRMD AIEGVNFSVG QGVLIPKLKS AESGTENK
//
