ID   Q8DNF7_STRR6            Unreviewed;       287 AA.
AC   Q8DNF7;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   27-MAR-2024, entry version 105.
DE   SubName: Full=Transcriptional activator {ECO:0000313|EMBL:AAL00566.1};
GN   Name=plcR {ECO:0000313|EMBL:AAL00566.1};
GN   OrderedLocusNames=spr1763 {ECO:0000313|EMBL:AAL00566.1};
OS   Streptococcus pneumoniae (strain ATCC BAA-255 / R6).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=171101 {ECO:0000313|EMBL:AAL00566.1, ECO:0000313|Proteomes:UP000000586};
RN   [1] {ECO:0000313|EMBL:AAL00566.1, ECO:0000313|Proteomes:UP000000586}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-255 / R6 {ECO:0000313|Proteomes:UP000000586};
RX   PubMed=11544234; DOI=10.1128/JB.183.19.5709-5717.2001;
RA   Hoskins J.A., Alborn W.Jr., Arnold J., Blaszczak L., Burgett S.,
RA   DeHoff B.S., Estrem S., Fritz L., Fu D.-J., Fuller W., Geringer C.,
RA   Gilmour R., Glass J.S., Khoja H., Kraft A., LaGace R., LeBlanc D.J.,
RA   Lee L.N., Lefkowitz E.J., Lu J., Matsushima P., McAhren S., McHenney M.,
RA   McLeaster K., Mundy C., Nicas T.I., Norris F.H., O'Gara M., Peery R.,
RA   Robertson G.T., Rockey P., Sun P.-M., Winkler M.E., Yang Y.,
RA   Young-Bellido M., Zhao G., Zook C., Baltz R.H., Jaskunas S.Richard.,
RA   Rosteck P.R.Jr., Skatrud P.L., Glass J.I.;
RT   "Genome of the bacterium Streptococcus pneumoniae strain R6.";
RL   J. Bacteriol. 183:5709-5717(2001).
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DR   EMBL; AE007317; AAL00566.1; -; Genomic_DNA.
DR   PIR; A99092; A99092.
DR   PIR; E95227; E95227.
DR   RefSeq; NP_359355.1; NC_003098.1.
DR   RefSeq; WP_001093641.1; NC_003098.1.
DR   AlphaFoldDB; Q8DNF7; -.
DR   SMR; Q8DNF7; -.
DR   STRING; 171101.spr1763; -.
DR   KEGG; spr:spr1763; -.
DR   PATRIC; fig|171101.6.peg.1905; -.
DR   eggNOG; COG1396; Bacteria.
DR   HOGENOM; CLU_053304_1_1_9; -.
DR   Proteomes; UP000000586; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR37038:SF14; TRANSCRIPTIONAL ACTIVATOR; 1.
DR   PANTHER; PTHR37038; TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR   Pfam; PF01381; HTH_3; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000586}.
FT   DOMAIN          8..61
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50943"
SQ   SEQUENCE   287 AA;  34130 MW;  C423FCFD36978859 CRC64;
     MNTLAEKFRL KRKELRLSQQ TLAEGICEQS QISKIERGHF IPSADLLFKL SQRLEVPLDY
     FFNEQIEVKS NLSNFKHLSA RLLDDRNYDD LEYLYKIEVE RSTFLTLEDR TYLEWIKSII
     DFYQYDSKCE AISSLENILL KVSSNTLIYL KALNTLSNFY SLVGREQEYE ANYSHLIELY
     QTKNLDHQEF LFGYIRVRYN YAHYLVSKEK YNEAIQEALE TIELCKQRQT SYQLAPLLIL
     VGNAGAKFLD REQVKNYYIE ARELCKIYNN PLMLMKIENY LKELDTV
//