ID Q8DRF6_STRR6 Unreviewed; 231 AA.
AC Q8DRF6;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 109.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:AAK98957.1};
DE EC=2.7.3.- {ECO:0000313|EMBL:AAK98957.1};
GN Name=hk07 {ECO:0000313|EMBL:AAK98957.1};
GN OrderedLocusNames=spr0153 {ECO:0000313|EMBL:AAK98957.1};
OS Streptococcus pneumoniae (strain ATCC BAA-255 / R6).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=171101 {ECO:0000313|EMBL:AAK98957.1, ECO:0000313|Proteomes:UP000000586};
RN [1] {ECO:0000313|EMBL:AAK98957.1, ECO:0000313|Proteomes:UP000000586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-255 / R6 {ECO:0000313|Proteomes:UP000000586};
RX PubMed=11544234; DOI=10.1128/JB.183.19.5709-5717.2001;
RA Hoskins J.A., Alborn W.Jr., Arnold J., Blaszczak L., Burgett S.,
RA DeHoff B.S., Estrem S., Fritz L., Fu D.-J., Fuller W., Geringer C.,
RA Gilmour R., Glass J.S., Khoja H., Kraft A., LaGace R., LeBlanc D.J.,
RA Lee L.N., Lefkowitz E.J., Lu J., Matsushima P., McAhren S., McHenney M.,
RA McLeaster K., Mundy C., Nicas T.I., Norris F.H., O'Gara M., Peery R.,
RA Robertson G.T., Rockey P., Sun P.-M., Winkler M.E., Yang Y.,
RA Young-Bellido M., Zhao G., Zook C., Baltz R.H., Jaskunas S.Richard.,
RA Rosteck P.R.Jr., Skatrud P.L., Glass J.I.;
RT "Genome of the bacterium Streptococcus pneumoniae strain R6.";
RL J. Bacteriol. 183:5709-5717(2001).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE007317; AAK98957.1; -; Genomic_DNA.
DR PIR; A97891; A97891.
DR RefSeq; NP_357747.2; NC_003098.1.
DR AlphaFoldDB; Q8DRF6; -.
DR STRING; 171101.spr0153; -.
DR KEGG; spr:spr0153; -.
DR PATRIC; fig|171101.6.peg.180; -.
DR eggNOG; COG2972; Bacteria.
DR HOGENOM; CLU_020473_2_2_9; -.
DR Proteomes; UP000000586; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16924; HATPase_YpdA-YehU-LytS-like; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR42713; HISTIDINE KINASE-RELATED; 1.
DR PANTHER; PTHR42713:SF2; TWO-COMPONENT SENSOR KINASE YESM; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AAK98957.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000586};
KW Transferase {ECO:0000313|EMBL:AAK98957.1}.
FT DOMAIN 22..99
FT /note="Signal transduction histidine kinase internal
FT region"
FT /evidence="ECO:0000259|Pfam:PF06580"
FT DOMAIN 120..229
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|Pfam:PF02518"
SQ SEQUENCE 231 AA; 27214 MW; B585C43424F90F78 CRC64;
MLDRLEKNIH DIYQLELSQK DANMRALQAQ INPHFMYNTL EFLRMYAVMQ SQDELADIIY
EFSSLLRNNI SDERETLLKQ ELEFCRKYSY LCMVRYPKSI AYGFKIDPEL ENMKIPKFTL
QPLVENYFAH GVDHRRTDNV ISIKALKQDG FVEILVVDNG RGMSAEKLAN IREKLSQKYF
EHQASYSDQR QSIGIVNVHE RFVLYFGDRY AITIESAEQA GVQYRITIQD E
//
