ID Q8DTX0_STRMU Unreviewed; 204 AA.
AC Q8DTX0;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE RecName: Full=TVP38/TMEM64 family membrane protein {ECO:0000256|RuleBase:RU366058};
GN OrderedLocusNames=SMU_1197 {ECO:0000313|EMBL:AAN58886.1};
OS Streptococcus mutans serotype c (strain ATCC 700610 / UA159).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=210007 {ECO:0000313|EMBL:AAN58886.1, ECO:0000313|Proteomes:UP000002512};
RN [1] {ECO:0000313|EMBL:AAN58886.1, ECO:0000313|Proteomes:UP000002512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700610 / UA159 {ECO:0000313|Proteomes:UP000002512};
RX PubMed=12397186; DOI=10.1073/pnas.172501299;
RA Ajdic D., McShan W.M., McLaughlin R.E., Savic G., Chang J., Carson M.B.,
RA Primeaux C., Tian R., Kenton S., Jia H., Lin S., Qian Y., Li S., Zhu H.,
RA Najar F., Lai H., White J., Roe B.A., Ferretti J.J.;
RT "Genome sequence of Streptococcus mutans UA159, a cariogenic dental
RT pathogen.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:14434-14439(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU366058};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU366058}.
CC -!- SIMILARITY: Belongs to the TVP38/TMEM64 family.
CC {ECO:0000256|RuleBase:RU366058}.
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DR EMBL; AE014133; AAN58886.1; -; Genomic_DNA.
DR RefSeq; NP_721580.1; NC_004350.2.
DR RefSeq; WP_002262154.1; NC_004350.2.
DR AlphaFoldDB; Q8DTX0; -.
DR STRING; 210007.SMU_1197; -.
DR DNASU; 1028496; -.
DR GeneID; 66817413; -.
DR KEGG; smu:SMU_1197; -.
DR PATRIC; fig|210007.7.peg.1074; -.
DR eggNOG; COG0398; Bacteria.
DR HOGENOM; CLU_038944_5_2_9; -.
DR OrthoDB; 371137at2; -.
DR PhylomeDB; Q8DTX0; -.
DR Proteomes; UP000002512; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR015414; TMEM64.
DR InterPro; IPR032816; VTT_dom.
DR PANTHER; PTHR12677:SF55; TVP38_TMEM64 FAMILY MEMBRANE PROTEIN; 1.
DR PANTHER; PTHR12677; UNCHARACTERIZED; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU366058};
KW Membrane {ECO:0000256|RuleBase:RU366058};
KW Reference proteome {ECO:0000313|Proteomes:UP000002512};
KW Transmembrane {ECO:0000256|RuleBase:RU366058};
KW Transmembrane helix {ECO:0000256|RuleBase:RU366058}.
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 55..74
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 81..111
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 143..165
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT DOMAIN 74..190
FT /note="VTT"
FT /evidence="ECO:0000259|Pfam:PF09335"
SQ SEQUENCE 204 AA; 23386 MW; C03A32258EEB573F CRC64;
MKVKLSKRYI LMQKIIQALG ILALIASVIL VIWFYKLGIL NDSNALKDLV HHHKVLGPLI
FILVQIFQIV FPVIPGGVTT VAGFLIFGTW LGFILNYIGI IIGSVLLFLL VKWLGRKFIL
LFMKEDTFYK YEAKLESDTY EKLFIFCMLS PVSPADIMVM ITGLTSMSLK RFTAIMVITK
PLSIICYSYF WIYGSKLLEF LFHK
//
