ID Q8E7Q6_STRA3 Unreviewed; 415 AA.
AC Q8E7Q6;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 124.
DE RecName: Full=HTH gntR-type domain-containing protein {ECO:0000259|PROSITE:PS50949};
GN OrderedLocusNames=gbs0098 {ECO:0000313|EMBL:CAD45743.1};
OS Streptococcus agalactiae serotype III (strain NEM316).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=211110 {ECO:0000313|EMBL:CAD45743.1};
RN [1] {ECO:0000313|EMBL:CAD45743.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEM316 {ECO:0000313|EMBL:CAD45743.1};
RX PubMed=12354221; DOI=10.1046/j.1365-2958.2002.03126.x;
RA Glaser P., Rusniok C., Buchrieser C., Chevalier F., Frangeul L., Msadek T.,
RA Zouine M., Couve E., Lalioui L., Poyart C., Trieu-Cuot P., Kunst F.;
RT "Genome sequence of Streptococcus agalactiae, a pathogen causing invasive
RT neonatal disease.";
RL Mol. Microbiol. 45:1499-1513(2002).
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
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DR EMBL; AL766843; CAD45743.1; -; Genomic_DNA.
DR RefSeq; WP_000256875.1; NC_004368.1.
DR AlphaFoldDB; Q8E7Q6; -.
DR KEGG; san:gbs0098; -.
DR eggNOG; COG1167; Bacteria.
DR HOGENOM; CLU_017584_0_0_9; -.
DR Proteomes; UP000000823; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..70
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 415 AA; 48185 MW; E27BDE7369A7BF37 CRC64;
MVTKVEEIRS YLIASIQNGK LAPGDRLPSI RQLANQFSCN KDTVQRVLME LRFDNYVYAK
PRSGYYVFDS HEEEVEEGVS LPNSEIANIA YDDFRLCLNE TLIGREDYLF NYYYRQEGLL
DLSKAVAKLM EETGVYVPLD DIVITAGTQQ ALFILTQVTF PNRKSRVLIE EPTYPRMIEL
IKTQNLPYET ISRGTHGIDF QRLEEIFQTQ SIKFFYVIPR MHNPLGTSYN PVEMKRLIEM
AEKYDVYIVE DDYMSDFASQ SPLHYYDTHG RVIYLKSFSK AIFPALRLAA ICLPQALKST
FMAYKKLMDY DTNLILQKAL ALYIENGLYG KNSQYLKYRY QKDLANSKSI LADQPNLPPY
SLHHDSVLFD CSKLDNFKIL RQYGDTLENY FCQKSHQSLL QVKNDSCLKQ FLGSL
//
