ID Q8EGQ7_SHEON Unreviewed; 335 AA.
AC Q8EGQ7;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 117.
DE SubName: Full=Isocitrate dehydrogenase NAD-dependent {ECO:0000313|EMBL:AAN54598.1};
DE EC=1.1.1.41 {ECO:0000313|EMBL:AAN54598.1};
GN OrderedLocusNames=SO_1538 {ECO:0000313|EMBL:AAN54598.1};
OS Shewanella oneidensis (strain MR-1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=211586 {ECO:0000313|EMBL:AAN54598.1, ECO:0000313|Proteomes:UP000008186};
RN [1] {ECO:0000313|EMBL:AAN54598.1, ECO:0000313|Proteomes:UP000008186}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR-1 {ECO:0000313|EMBL:AAN54598.1,
RC ECO:0000313|Proteomes:UP000008186};
RX PubMed=12368813; DOI=10.1038/nbt749;
RA Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C.,
RA Read T.D., Eisen J.A., Seshadri R., Ward N., Methe B., Clayton R.A.,
RA Meyer T., Tsapin A., Scott J., Beanan M., Brinkac L., Daugherty S.,
RA DeBoy R.T., Dodson R.J., Durkin A.S., Haft D.H., Kolonay J.F., Madupu R.,
RA Peterson J.D., Umayam L.A., White O., Wolf A.M., Vamathevan J., Weidman J.,
RA Impraim M., Lee K., Berry K., Lee C., Mueller J., Khouri H., Gill J.,
RA Utterback T.R., McDonald L.A., Feldblyum T.V., Smith H.O., Venter J.C.,
RA Nealson K.H., Fraser C.M.;
RT "Genome sequence of the dissimilatory metal ion-reducing bacterium
RT Shewanella oneidensis.";
RL Nat. Biotechnol. 20:1118-1123(2002).
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
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DR EMBL; AE014299; AAN54598.1; -; Genomic_DNA.
DR RefSeq; NP_717154.1; NC_004347.2.
DR RefSeq; WP_011071715.1; NZ_CP053946.1.
DR AlphaFoldDB; Q8EGQ7; -.
DR STRING; 211586.SO_1538; -.
DR PaxDb; 211586-SO_1538; -.
DR KEGG; son:SO_1538; -.
DR PATRIC; fig|211586.12.peg.1481; -.
DR eggNOG; COG0473; Bacteria.
DR HOGENOM; CLU_031953_0_1_6; -.
DR OrthoDB; 9806254at2; -.
DR PhylomeDB; Q8EGQ7; -.
DR BioCyc; SONE211586:G1GMP-1420-MONOMER; -.
DR Proteomes; UP000008186; Chromosome.
DR GO; GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IBA:GO_Central.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0006102; P:isocitrate metabolic process; IBA:GO_Central.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IBA:GO_Central.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR PANTHER; PTHR11835:SF34; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR PROSITE; PS00470; IDH_IMDH; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:AAN54598.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008186}.
FT DOMAIN 5..331
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
SQ SEQUENCE 335 AA; 36024 MW; F888C4E96C881880 CRC64;
MSKRTITVIP GDGIGPSIID SALKILDKAG CDFEYEFADA GLAALEKQGE LLPQRTLELI
EKNRITLKGP LTTPVGEGFT SINVTLRKKF GLYANVRPVL SFKGTQARYE NIDIITVREN
TEGMYSGHGQ KVSEDGSTAE ATSIVTRQGA EQIATFAYEL ARKESRKKVT IVHKANIMKS
TSGLFLKVAR EVSLRYPDIK TEEMIVDATC MKLVMNPENF DVIVTTNLFG DILSDLCAGL
VGGLGMAPGA NIGRDAAIFE AVHGSAPDIA GKNLANPTSV ILASIQMLEY LGMADKAAPI
RKAVSAVIEE GDRTTRDLGG THGTTDFTQA VLDRL
//
