ID Q8EMC3_OCEIH Unreviewed; 437 AA.
AC Q8EMC3;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 116.
DE SubName: Full=Vi polysaccharide biosynthesis {ECO:0000313|EMBL:BAC14887.1};
GN OrderedLocusNames=OB2931 {ECO:0000313|EMBL:BAC14887.1};
OS Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC
OS 3954 / HTE831).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Oceanobacillus.
OX NCBI_TaxID=221109 {ECO:0000313|EMBL:BAC14887.1, ECO:0000313|Proteomes:UP000000822};
RN [1] {ECO:0000313|EMBL:BAC14887.1, ECO:0000313|Proteomes:UP000000822}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831
RC {ECO:0000313|Proteomes:UP000000822};
RX PubMed=12235376; DOI=10.1093/nar/gkf526;
RA Takami H., Takaki Y., Uchiyama I.;
RT "Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge
RT and its unexpected adaptive capabilities to extreme environments.";
RL Nucleic Acids Res. 30:3927-3935(2002).
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; BA000028; BAC14887.1; -; Genomic_DNA.
DR RefSeq; WP_011067328.1; NC_004193.1.
DR AlphaFoldDB; Q8EMC3; -.
DR STRING; 221109.gene:10735183; -.
DR KEGG; oih:OB2931; -.
DR eggNOG; COG0677; Bacteria.
DR HOGENOM; CLU_023810_3_1_9; -.
DR OrthoDB; 9803238at2; -.
DR PhylomeDB; Q8EMC3; -.
DR Proteomes; UP000000822; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000000822}.
FT DOMAIN 322..424
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 437 AA; 48327 MW; 043EE05C5F02FFE0 CRC64;
MSLFEKIQNK TEKIAVIGLG YVGLPLAVEL AKKYDVIGLD LNKEKLAQYS NGIDVTAEVG
NEALKQTTLE FTSDETRLKE CKFHIVAVPT PINTDKTPNL KPVIGASESV GRNISKGSIV
VYESTVYPGT TEEICIPILE EKSGLKFGQD FKVGYSPERI NPGDKVNTLV SITKVVSGSD
EDALKEISSL YGSIIEAGVF EAESIKVAEA AKVIENSQRD INIAFMNELS MVFNKMDIDT
KAVLEAAGTK WNFLNFTPGL VGGHCIGVDP YYFTYKAEQL GYHSQIILSG RKINDDMGKY
IAGNIIKKMI KSKIEIDGAR VAILGLTFKE NVGDVRNTKV NDIVTELEEY GVNVIVHDPV
AEGQEVKKVF GIELAEEDDL QDLDAVVLAV PHQHYKELNV NKINTMYRQD NKKVFIDIKG
SLDKNDFYQA GYSYWSL
//
