ID Q8EPC3_OCEIH Unreviewed; 365 AA.
AC Q8EPC3;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE SubName: Full=Xaa-Pro dipeptidase {ECO:0000313|EMBL:BAC14143.1};
DE EC=3.4.13.9 {ECO:0000313|EMBL:BAC14143.1};
GN OrderedLocusNames=OB2187 {ECO:0000313|EMBL:BAC14143.1};
OS Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC
OS 3954 / HTE831).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Oceanobacillus.
OX NCBI_TaxID=221109 {ECO:0000313|EMBL:BAC14143.1, ECO:0000313|Proteomes:UP000000822};
RN [1] {ECO:0000313|EMBL:BAC14143.1, ECO:0000313|Proteomes:UP000000822}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831
RC {ECO:0000313|Proteomes:UP000000822};
RX PubMed=12235376; DOI=10.1093/nar/gkf526;
RA Takami H., Takaki Y., Uchiyama I.;
RT "Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge
RT and its unexpected adaptive capabilities to extreme environments.";
RL Nucleic Acids Res. 30:3927-3935(2002).
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
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DR EMBL; BA000028; BAC14143.1; -; Genomic_DNA.
DR RefSeq; WP_011066581.1; NC_004193.1.
DR AlphaFoldDB; Q8EPC3; -.
DR STRING; 221109.gene:10734435; -.
DR KEGG; oih:OB2187; -.
DR eggNOG; COG0006; Bacteria.
DR HOGENOM; CLU_017266_4_2_9; -.
DR OrthoDB; 9806388at2; -.
DR PhylomeDB; Q8EPC3; -.
DR Proteomes; UP000000822; Chromosome.
DR GO; GO:0102009; F:proline dipeptidase activity; IEA:UniProtKB-EC.
DR CDD; cd01092; APP-like; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR PANTHER; PTHR46112; AMINOPEPTIDASE; 1.
DR PANTHER; PTHR46112:SF10; DIPEPTIDASE YKVY-RELATED; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 4: Predicted;
KW Dipeptidase {ECO:0000313|EMBL:BAC14143.1};
KW Hydrolase {ECO:0000313|EMBL:BAC14143.1};
KW Protease {ECO:0000313|EMBL:BAC14143.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000822}.
FT DOMAIN 4..138
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 146..348
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
SQ SEQUENCE 365 AA; 41215 MW; E1C18AC03D333004 CRC64;
MQERLENFLN KLKEQTIDSA FITSKANVYY LSNYYTEPHE RIVGIYLSEN FDPIFLLPKM
EESDARNAGW KYTILSYYDH ENPWEILKDY LNKQNHQPQS VALEQDHITM DRYQAIQNTL
PEAQFQDAKE ILAQLRVIKS DKELSLLKTA AELADFGIQT GVETIQEGIS ELDLVATIEY
SLKKQGIREM SFQTMALSGA KTASPHGHPS TSKLEKNGFV LFDLGVIYQG YCSDITRTVA
FGNLTEEQKN VYETVLNAEE AAIEKSVVGT SVGVIDQTAR KVINDAGYGE YFTHRIGHGL
GIETHEYPSM HGENNLPLQS GMTFTIEPGI YVPNVGGVRI EDMIHMTEEG PKTLTKYPKN
LQIVN
//
