ID Q8ETJ0_OCEIH Unreviewed; 424 AA.
AC Q8ETJ0;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN OrderedLocusNames=OB0270 {ECO:0000313|EMBL:BAC12226.1};
OS Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC
OS 3954 / HTE831).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Oceanobacillus.
OX NCBI_TaxID=221109 {ECO:0000313|EMBL:BAC12226.1, ECO:0000313|Proteomes:UP000000822};
RN [1] {ECO:0000313|EMBL:BAC12226.1, ECO:0000313|Proteomes:UP000000822}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831
RC {ECO:0000313|Proteomes:UP000000822};
RX PubMed=12235376; DOI=10.1093/nar/gkf526;
RA Takami H., Takaki Y., Uchiyama I.;
RT "Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge
RT and its unexpected adaptive capabilities to extreme environments.";
RL Nucleic Acids Res. 30:3927-3935(2002).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
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DR EMBL; BA000028; BAC12226.1; -; Genomic_DNA.
DR RefSeq; WP_011064672.1; NC_004193.1.
DR AlphaFoldDB; Q8ETJ0; -.
DR STRING; 221109.gene:10732473; -.
DR CAZy; GH3; Glycoside Hydrolase Family 3.
DR KEGG; oih:OB0270; -.
DR eggNOG; COG1472; Bacteria.
DR HOGENOM; CLU_008392_0_2_9; -.
DR OrthoDB; 9805821at2; -.
DR PhylomeDB; Q8ETJ0; -.
DR Proteomes; UP000000822; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR019800; Glyco_hydro_3_AS.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000822};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 53..374
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
SQ SEQUENCE 424 AA; 46283 MW; C8F29B75475CE9E1 CRC64;
MKWISSIVIM AVITVGVVYY YLQSGDEKTN HSNHNTSMGG TLDVSSLVDA MSLDEKIGQL
IVGGIDGTEI NTDTKDMIEN YHVGGVILFA DNIESKAQTV NLMNDIKQVN ENNPHPLLLG
VDEEGGSVTR MPDEITSLPP SGSIGKAQDE ELAFEVGILL GQQMRGLGFN LNFAPVLDVN
SNPDNPVIGD RSFGDSPDIV TDMGIQSMKG IQSEGIISVV KHFPGHGDTS EDSHLKLPKV
DKSIEELSEV ELVPFEKAIS KGADVVMTAH ILLPQIDTEY PASMSEKIIS GLLREDMGFD
GVVISDDLTM GAITENIRIE EAAIQSVKAG SDMVLIAHHP DVVVSVHKKL KAAVQNGVIS
EAKIDESVER IIQLKRKYKL SNEETPQIDF QRINEKVEEI LDQVSSTFSF DEFLVYSKFM
SIVL
//
