ID Q8EZ78_LEPIN Unreviewed; 143 AA.
AC Q8EZ78;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=Lysine methyltransferase {ECO:0000313|EMBL:AAN51176.1};
GN OrderedLocusNames=LA_3978 {ECO:0000313|EMBL:AAN51176.1};
OS Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain
OS 56601).
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=189518 {ECO:0000313|EMBL:AAN51176.1, ECO:0000313|Proteomes:UP000001408};
RN [1] {ECO:0000313|EMBL:AAN51176.1, ECO:0000313|Proteomes:UP000001408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=56601 {ECO:0000313|EMBL:AAN51176.1,
RC ECO:0000313|Proteomes:UP000001408};
RX PubMed=12712204; DOI=10.1038/nature01597;
RA Ren S.X., Fu G., Jiang X.G., Zeng R., Miao Y.G., Xu H., Zhang Y.X.,
RA Xiong H., Lu G., Lu L.F., Jiang H.Q., Jia J., Tu Y.F., Jiang J.X., Gu W.Y.,
RA Zhang Y.Q., Cai Z., Sheng H.H., Yin H.F., Zhang Y., Zhu G.F., Wan M.,
RA Huang H.L., Qian Z., Wang S.Y., Ma W., Yao Z.J., Shen Y., Qiang B.Q.,
RA Xia Q.C., Guo X.K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.M.,
RA Shi M.H., Chen Z., Xu J.G., Zhao G.P.;
RT "Unique physiological and pathogenic features of Leptospira interrogans
RT revealed by whole-genome sequencing.";
RL Nature 422:888-893(2003).
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DR EMBL; AE010300; AAN51176.1; -; Genomic_DNA.
DR RefSeq; NP_714158.1; NC_004342.2.
DR RefSeq; WP_001177028.1; NC_004342.2.
DR AlphaFoldDB; Q8EZ78; -.
DR STRING; 189518.LA_3978; -.
DR PaxDb; 189518-LA_3978; -.
DR EnsemblBacteria; AAN51176; AAN51176; LA_3978.
DR GeneID; 61143047; -.
DR KEGG; lil:LA_3978; -.
DR PATRIC; fig|189518.3.peg.3948; -.
DR HOGENOM; CLU_137658_0_0_12; -.
DR InParanoid; Q8EZ78; -.
DR OrthoDB; 9790349at2; -.
DR Proteomes; UP000001408; Chromosome I.
DR GO; GO:0042054; F:histone methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR045318; EZH1/2-like.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR45747; HISTONE-LYSINE N-METHYLTRANSFERASE E(Z); 1.
DR PANTHER; PTHR45747:SF4; HISTONE-LYSINE N-METHYLTRANSFERASE E(Z); 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:AAN51176.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001408};
KW Transferase {ECO:0000313|EMBL:AAN51176.1}.
FT DOMAIN 16..128
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
SQ SEQUENCE 143 AA; 16839 MW; DB9F412EBFF556F1 CRC64;
MQLRKKTSRS HIFHEKDFEI KPSSIPGIGM GLFPKENVNK GDTIGYYTGK ILTDRTANSS
KYCESKYLLW ICKDHWIYGE GKESNYTRFM NHSSKPNVRL VVSVRWKTAR FEAIRKIKSG
EELFFDYGDE YWINTDIDPI ERN
//
