ID Q8EZF1_LEPIN Unreviewed; 288 AA.
AC Q8EZF1;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Metallo-beta-lactamase superfamily hydrolase {ECO:0000313|EMBL:AAN51101.1};
GN OrderedLocusNames=LA_3903 {ECO:0000313|EMBL:AAN51101.1};
OS Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain
OS 56601).
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=189518 {ECO:0000313|EMBL:AAN51101.1, ECO:0000313|Proteomes:UP000001408};
RN [1] {ECO:0000313|EMBL:AAN51101.1, ECO:0000313|Proteomes:UP000001408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=56601 {ECO:0000313|EMBL:AAN51101.1,
RC ECO:0000313|Proteomes:UP000001408};
RX PubMed=12712204; DOI=10.1038/nature01597;
RA Ren S.X., Fu G., Jiang X.G., Zeng R., Miao Y.G., Xu H., Zhang Y.X.,
RA Xiong H., Lu G., Lu L.F., Jiang H.Q., Jia J., Tu Y.F., Jiang J.X., Gu W.Y.,
RA Zhang Y.Q., Cai Z., Sheng H.H., Yin H.F., Zhang Y., Zhu G.F., Wan M.,
RA Huang H.L., Qian Z., Wang S.Y., Ma W., Yao Z.J., Shen Y., Qiang B.Q.,
RA Xia Q.C., Guo X.K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.M.,
RA Shi M.H., Chen Z., Xu J.G., Zhao G.P.;
RT "Unique physiological and pathogenic features of Leptospira interrogans
RT revealed by whole-genome sequencing.";
RL Nature 422:888-893(2003).
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DR EMBL; AE010300; AAN51101.1; -; Genomic_DNA.
DR RefSeq; NP_714083.1; NC_004342.2.
DR RefSeq; WP_000013300.1; NC_004342.2.
DR AlphaFoldDB; Q8EZF1; -.
DR STRING; 189518.LA_3903; -.
DR PaxDb; 189518-LA_3903; -.
DR EnsemblBacteria; AAN51101; AAN51101; LA_3903.
DR KEGG; lil:LA_3903; -.
DR PATRIC; fig|189518.3.peg.3871; -.
DR HOGENOM; CLU_056853_1_0_12; -.
DR InParanoid; Q8EZF1; -.
DR OrthoDB; 9802248at2; -.
DR Proteomes; UP000001408; Chromosome I.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd07727; YmaE-like_MBL-fold; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR42773:SF1; METALLO-BETA-LACTAMASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR42773; METALLO-BETA-LACTAMASE-RELATED; 1.
DR Pfam; PF13370; Fer4_13; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AAN51101.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001408}.
FT DOMAIN 105..263
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 288 AA; 33141 MW; 108DD1FD96E3C944 CRC64;
MANQLKKRPE NQEGNFYVDS TCIDCETCRI VAPKTFAEKN GGSYVWKQPE IESEKIAALR
ALIACPTTSI GTINRIDLKE AKETFPSKIE ENVYYCGYHS KDSFGAFSYL ILRENGNILV
DSPRFVSSLA DKIESLGGIR YHFLTHQDDV ADHQKFKEKF GCDRIIHEND LKSLPSAEIV
LKGEKVFELD NEVKMIPVPG HTQGHSVLLY KNRFLFTGDH LAYDPLKDRL IAFKNVCWYS
WQEQINSMKK LKNYSFEWVL PGHGYPVNKE QKIMLDLLKS CIAWMETR
//
