ID Q8F4V3_LEPIN Unreviewed; 623 AA.
AC Q8F4V3;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=Hydrolase or acyltransferase {ECO:0000313|EMBL:AAN49135.1};
GN OrderedLocusNames=LA_1936 {ECO:0000313|EMBL:AAN49135.1};
OS Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain
OS 56601).
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=189518 {ECO:0000313|EMBL:AAN49135.1, ECO:0000313|Proteomes:UP000001408};
RN [1] {ECO:0000313|EMBL:AAN49135.1, ECO:0000313|Proteomes:UP000001408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=56601 {ECO:0000313|EMBL:AAN49135.1,
RC ECO:0000313|Proteomes:UP000001408};
RX PubMed=12712204; DOI=10.1038/nature01597;
RA Ren S.X., Fu G., Jiang X.G., Zeng R., Miao Y.G., Xu H., Zhang Y.X.,
RA Xiong H., Lu G., Lu L.F., Jiang H.Q., Jia J., Tu Y.F., Jiang J.X., Gu W.Y.,
RA Zhang Y.Q., Cai Z., Sheng H.H., Yin H.F., Zhang Y., Zhu G.F., Wan M.,
RA Huang H.L., Qian Z., Wang S.Y., Ma W., Yao Z.J., Shen Y., Qiang B.Q.,
RA Xia Q.C., Guo X.K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.M.,
RA Shi M.H., Chen Z., Xu J.G., Zhao G.P.;
RT "Unique physiological and pathogenic features of Leptospira interrogans
RT revealed by whole-genome sequencing.";
RL Nature 422:888-893(2003).
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DR EMBL; AE010300; AAN49135.1; -; Genomic_DNA.
DR RefSeq; NP_712117.1; NC_004342.2.
DR RefSeq; WP_000929340.1; NC_004342.2.
DR AlphaFoldDB; Q8F4V3; -.
DR STRING; 189518.LA_1936; -.
DR ESTHER; lepin-LA1936; 6_AlphaBeta_hydrolase.
DR PaxDb; 189518-LA_1936; -.
DR EnsemblBacteria; AAN49135; AAN49135; LA_1936.
DR GeneID; 61141862; -.
DR KEGG; lil:LA_1936; -.
DR PATRIC; fig|189518.3.peg.1924; -.
DR HOGENOM; CLU_438562_0_0_12; -.
DR InParanoid; Q8F4V3; -.
DR OrthoDB; 334691at2; -.
DR Proteomes; UP000001408; Chromosome I.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016298; F:lipase activity; IBA:GO_Central.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR PANTHER; PTHR11614:SF87; MONOGLYCERIDE LIPASE; 1.
DR PANTHER; PTHR11614; PHOSPHOLIPASE-RELATED; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:AAN49135.1};
KW Hydrolase {ECO:0000313|EMBL:AAN49135.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001408};
KW Transferase {ECO:0000313|EMBL:AAN49135.1}.
FT DOMAIN 295..604
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
SQ SEQUENCE 623 AA; 71151 MW; 0609C46FA3C4F97F CRC64;
MAGVLEKKNT SRKRRGKSGL NVAADDIFIF PIPGTTYKFV EKVWSSFVNK FVALTFTNNQ
PVFNYAVFEA IQDKNLKIVA SATHFKMKEI ATRIGLRDIQ EFINRTLPVS IQDQDNLSAN
FIREAIISVE TKKRPEVVFS SLKDDKIHPN LRHLLSGTMN YAAGIPLFVK GNPIGMIWGI
RRDRMSDEQR EEVREQLSSF YDVVDFVVAR EMDNKADPYI AKKNIEKADL HSYAKHLYYT
RTGGQQHPVT SIIFDCHTYN CSYRLDASYI IPSNNGFSVS LKRFEPEKTN GTGKILLLIP
GFFCRRSVMD KVAREMALKY GYRVFSMDMR GRSRQTLPYN GIKEGWTIDD FIQEDFPAVL
NWIRESFPKE KIVVMGHSMG GMIPRYYVSA YETFIAKYPQ NKVSLPDPKE TISGIISVTS
PNFVSVGTNI PGMSALKTGL SLLPAKSISD FLFDITTFSL QSTLPTVDLN KFFKFLLGLH
SSLRTVSFEL STKVVNLRDF VGYRQISPPE WYFLIEDIFC EESTKVILQF IRSQLSKDHA
FFSFDGSINY TELQRNFQLP IYSVLGTLDK IVPVNSVEEE LRALPSSNNQ IVKFDQGHLG
ILFHMPTVRE MCAGFHDWIQ KLD
//
