ID Q8F8Z9_LEPIN Unreviewed; 353 AA.
AC Q8F8Z9;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Paraoxonase {ECO:0000313|EMBL:AAN47598.1};
GN OrderedLocusNames=LA_0399 {ECO:0000313|EMBL:AAN47598.1};
OS Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain
OS 56601).
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=189518 {ECO:0000313|EMBL:AAN47598.1, ECO:0000313|Proteomes:UP000001408};
RN [1] {ECO:0000313|EMBL:AAN47598.1, ECO:0000313|Proteomes:UP000001408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=56601 {ECO:0000313|EMBL:AAN47598.1,
RC ECO:0000313|Proteomes:UP000001408};
RX PubMed=12712204; DOI=10.1038/nature01597;
RA Ren S.X., Fu G., Jiang X.G., Zeng R., Miao Y.G., Xu H., Zhang Y.X.,
RA Xiong H., Lu G., Lu L.F., Jiang H.Q., Jia J., Tu Y.F., Jiang J.X., Gu W.Y.,
RA Zhang Y.Q., Cai Z., Sheng H.H., Yin H.F., Zhang Y., Zhu G.F., Wan M.,
RA Huang H.L., Qian Z., Wang S.Y., Ma W., Yao Z.J., Shen Y., Qiang B.Q.,
RA Xia Q.C., Guo X.K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.M.,
RA Shi M.H., Chen Z., Xu J.G., Zhao G.P.;
RT "Unique physiological and pathogenic features of Leptospira interrogans
RT revealed by whole-genome sequencing.";
RL Nature 422:888-893(2003).
CC -!- SIMILARITY: Belongs to the paraoxonase family.
CC {ECO:0000256|ARBA:ARBA00008595}.
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DR EMBL; AE010300; AAN47598.1; -; Genomic_DNA.
DR RefSeq; NP_710580.1; NC_004342.2.
DR RefSeq; WP_000917836.1; NC_004342.2.
DR AlphaFoldDB; Q8F8Z9; -.
DR STRING; 189518.LA_0399; -.
DR PaxDb; 189518-LA_0399; -.
DR EnsemblBacteria; AAN47598; AAN47598; LA_0399.
DR KEGG; lil:LA_0399; -.
DR PATRIC; fig|189518.3.peg.406; -.
DR HOGENOM; CLU_049839_1_0_12; -.
DR InParanoid; Q8F8Z9; -.
DR OrthoDB; 338518at2; -.
DR Proteomes; UP000001408; Chromosome I.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004064; F:arylesterase activity; IEA:InterPro.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR002640; Arylesterase.
DR PANTHER; PTHR11799; PARAOXONASE; 1.
DR PANTHER; PTHR11799:SF12; PARAOXONASE-RELATED; 1.
DR Pfam; PF01731; Arylesterase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001408};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 353 AA; 40178 MW; DFA333273307C9A8 CRC64;
MLKQTEKSEN YLLSLLGMIL FIIFGLFNCG VEINPSGPSG ADCKKIEGLP GPEDLAIDRE
EKILYISSHE KRIKNQTGKI FKIDLKNPSA TPEEILVKYP SEFRPHGISL LKTKNTYRLY
VISHPEFFKI HTIEIFERKG KEWFHVGTLT DPLLTNPNDL SVVSENEIYL SNDHGKGNIL
RYLWDDLFQI KRSEISYYDG KTWSNLGNPL SFGNGILYTK DSQGNEFLYR SGYMDQSVFQ
FQIRREQGKP ILGKPKRILI NFGPDNLEID SKGRIFAVTH GSGYQFLRHI GNPEYLSPTI
VFRISSDGTF QEVFANSGDL ISAGSTAIPF EGRLYIAQVF NPYILNCEYS NSD
//
