ID Q8GE51_HELMO Unreviewed; 630 AA.
AC Q8GE51;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Exconuclease ABC subunit C {ECO:0000313|EMBL:AAN87371.1};
DE Flags: Fragment;
OS Heliobacterium mobile (Heliobacillus mobilis).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Heliobacteriaceae;
OC Heliobacterium.
OX NCBI_TaxID=28064 {ECO:0000313|EMBL:AAN87371.1};
RN [1] {ECO:0000313|EMBL:AAN87371.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12446909; DOI=10.1126/science.1075558;
RA Raymond J., Zhaxybayeva O., Gogarten J.P., Gerdes S.Y., Blankenship R.E.;
RT "Whole-genome analysis of photosynthetic prokaryotes.";
RL Science 298:1616-1620(2002).
RN [2] {ECO:0000313|EMBL:AAN87371.1}
RP NUCLEOTIDE SEQUENCE.
RA Liolios K.G., Chu L., Ostrovskaya O., Mendybaeva N., Koukharenko V.,
RA Gerdes S., Kyrpides N., Overbeek R.;
RL Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AY142767; AAN87371.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8GE51; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0009381; F:excinuclease ABC activity; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd10434; GIY-YIG_UvrC_Cho; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.1440.10; GIY-YIG endonuclease; 1.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR Gene3D; 3.30.420.340; UvrC, RNAse H endonuclease domain; 1.
DR HAMAP; MF_00203; UvrC; 1.
DR InterPro; IPR000305; GIY-YIG_endonuc.
DR InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR InterPro; IPR047296; GIY-YIG_UvrC_Cho.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR001943; UVR_dom.
DR InterPro; IPR036876; UVR_dom_sf.
DR InterPro; IPR004791; UvrC.
DR InterPro; IPR001162; UvrC_RNase_H_dom.
DR InterPro; IPR038476; UvrC_RNase_H_dom_sf.
DR NCBIfam; TIGR00194; uvrC; 1.
DR PANTHER; PTHR30562:SF1; UVRABC SYSTEM PROTEIN C; 1.
DR PANTHER; PTHR30562; UVRC/OXIDOREDUCTASE; 1.
DR Pfam; PF01541; GIY-YIG; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF02151; UVR; 1.
DR Pfam; PF08459; UvrC_RNaseH_dom; 1.
DR SMART; SM00465; GIYc; 1.
DR SMART; SM00278; HhH1; 2.
DR SUPFAM; SSF46600; C-terminal UvrC-binding domain of UvrB; 1.
DR SUPFAM; SSF82771; GIY-YIG endonuclease; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
DR PROSITE; PS50164; GIY_YIG; 1.
DR PROSITE; PS50151; UVR; 1.
DR PROSITE; PS50165; UVRC; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881}.
FT DOMAIN 14..93
FT /note="GIY-YIG"
FT /evidence="ECO:0000259|PROSITE:PS50164"
FT DOMAIN 203..238
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT DOMAIN 254..500
FT /note="UvrC family homology region profile"
FT /evidence="ECO:0000259|PROSITE:PS50165"
FT COILED 206..252
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 352..379
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 630
FT /evidence="ECO:0000313|EMBL:AAN87371.1"
SQ SEQUENCE 630 AA; 72809 MW; 12F50B54AD09ACCE CRC64;
MHLTLQEKLK NLPDRPGVYL MKDETGRVIY VGKAINLKNR VRSYFQSAKN LTAKTQALVA
RIQDLETIVT DSELEALILE CNLIKEHKPR YNIMLRDDKT YPYLKVTLQE TYPRLLMTRR
LEKDGGKYFG PYTSAGAVRE TLNLLRSIFP LRTCSRKDFD QRKRPCLNYH IGRCLAPCFG
KVSRDEYMHM LKNIIAFLEG KEDDLLRRLR EEMHQAAEDL EFERAAELRN RIQALEQVME
KQKVVSTDLE DQDVIAMARG FNQVCVQIFF IRGGKLIGRE HFILEGTDEM ERSEVITAFV
KQYYSRSEFV PREILLQEPL ESQEEEEVLS RFLKEKRKGK VEIRVPKRGD KLKLIEMVAK
NALLTLEQLQ NEQQRKKSMT EEAVLDLQRY LALEEPPWRI ECFDISNTMG KESVASMVVF
EGGAPKNAEY RRFRIKTVDG PNDFASMQEV LNRRFSRARE EAQAVEEGQL DPMSAKFAVL
PDLIIVDGGK GQLSSARETL RRVGYDYIPT FGLAKENEWL FHESSSEPII LPRGSRSLYL
VQRIRDEAHR FAITYHRKLR AQAQTASVLD EISGIGPKRK TALLRHFGSV KKIAEATLEQ
LAAVDGMNVE IAERVLNHFR AREKETKVAE
//
