ID WOX12_ARATH Reviewed; 268 AA.
AC Q8GY25; Q9FN71;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 129.
DE RecName: Full=WUSCHEL-related homeobox 12;
GN Name=WOX12; OrderedLocusNames=At5g17810; ORFNames=MVA3.160, MVA3.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Landsberg erecta;
RX PubMed=14711878; DOI=10.1242/dev.00963;
RA Haecker A., Gross-Hardt R., Geiges B., Sarkar A., Breuninger H.,
RA Herrmann M., Laux T.;
RT "Expression dynamics of WOX genes mark cell fate decisions during early
RT embryonic patterning in Arabidopsis thaliana.";
RL Development 131:657-668(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9405937; DOI=10.1093/dnares/4.4.291;
RA Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence
RT features of the regions of 1,044,062 bp covered by thirteen physically
RT assigned P1 clones.";
RL DNA Res. 4:291-300(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: Transcription factor which may be involved in developmental
CC processes. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
CC -!- SIMILARITY: Belongs to the WUS homeobox family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB09580.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AY251403; AAP37141.1; -; mRNA.
DR EMBL; AB006706; BAB09580.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED92472.1; -; Genomic_DNA.
DR EMBL; CP002688; AED92473.1; -; Genomic_DNA.
DR EMBL; AK117910; BAC42548.1; -; mRNA.
DR EMBL; BT006232; AAP12881.1; -; mRNA.
DR RefSeq; NP_001190327.1; NM_001203398.1.
DR RefSeq; NP_197283.2; NM_121787.3.
DR AlphaFoldDB; Q8GY25; -.
DR SMR; Q8GY25; -.
DR BioGRID; 16925; 1.
DR IntAct; Q8GY25; 1.
DR STRING; 3702.Q8GY25; -.
DR PaxDb; 3702-AT5G17810-2; -.
DR EnsemblPlants; AT5G17810.1; AT5G17810.1; AT5G17810.
DR EnsemblPlants; AT5G17810.2; AT5G17810.2; AT5G17810.
DR GeneID; 831649; -.
DR Gramene; AT5G17810.1; AT5G17810.1; AT5G17810.
DR Gramene; AT5G17810.2; AT5G17810.2; AT5G17810.
DR KEGG; ath:AT5G17810; -.
DR Araport; AT5G17810; -.
DR TAIR; AT5G17810; WOX12.
DR eggNOG; ENOG502QUIQ; Eukaryota.
DR HOGENOM; CLU_030463_0_0_1; -.
DR InParanoid; Q8GY25; -.
DR OMA; ENLFTMY; -.
DR OrthoDB; 1100416at2759; -.
DR PhylomeDB; Q8GY25; -.
DR PRO; PR:Q8GY25; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q8GY25; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0048830; P:adventitious root development; IGI:TAIR.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR044558; WOX11-like.
DR PANTHER; PTHR46998; WUSCHEL-RELATED HOMEOBOX 11; 1.
DR PANTHER; PTHR46998:SF5; WUSCHEL-RELATED HOMEOBOX 12; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..268
FT /note="WUSCHEL-related homeobox 12"
FT /id="PRO_0000049379"
FT DNA_BIND 17..81
FT /note="Homeobox; WUS-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 173..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 268 AA; 29714 MW; CBF00D6C9A681B4C CRC64;
MNQEGASHSP SSTSTEPVRA RWSPKPEQIL ILESIFNSGT VNPPKDETVR IRKMLEKFGA
VGDANVFYWF QNRRSRSRRR HRQLLAATTA AATSIGAEDH QHMTAMSMHQ YPCSNNEIDL
GFGSCSNLSA NYFLNGSSSS QIPSFFLGLS SSSGGCENNN GMENLFKMYG HESDHNHQQQ
HHSSNAASVL NPSDQNSNSQ YEQEGFMTVF INGVPMEVTK GAIDMKTMFG DDSVLLHSSG
LPLPTDEFGF LMHSLQHGQT YFLVPRQT
//
